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The objective of this study was to clarify the relative roles of medial versus luminal factors in the induction of thickening of the arterial intima after balloon angioplasty injury. Platelet-derived growth factor (PDGF) and thrombin, both associated with ...
The aim of this study is to evaluate the relative importance of elastic non-linearities, viscoelasticity and resistance vessel modelling on arterial pressure and flow wave contours computed with distributed arterial network models. The computational result ...
The fluid flow through a tube with an oscillating elliptical cross-section was analyzed in order to understand better the effects of lateral deformation and movement on flow patterns in large and medium-sized blood vessels. Time-dependent elliptical deform ...
We propose a new, simple way of constructing elastic tubes which can be used to model the nonlinear elastic properties of large arteries. The tube models are constructed from a silicon elastomer (Sylgard 184, Dow Corning), which exhibits a nonlinear behavi ...
In view of the evidence linking plasma high density lipoprotein (HDL)-cholesterol levels to a protective effect against coronary artery disease and the widespread use of fibrates in the treatment of hyperlipidemia, the goal of this study was to analyze the ...
We tested the hypothesis that the cytosolic free calcium concentration in endothelial cells is under the influence of the smooth muscle cells in the coronary circulation. In the left descending branch of porcine coronary arteries, cytosolic free calcium co ...
Blood flow patterns in the coronary arteries are of interest due to their possible involvement in atherosclerosis localization. Spatial variations in hemodynamic flow patterns are predominantly determined by the vessel geometry. The coronary arteries repre ...
This study addressed the possible influence of apolipoprotein E (apo E) genotype on age-related changes in total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), and triglyceride (TG) levels in older males. Apo E is a component of LDL, is a l ...
This study is concerned with the wave reflection properties of arterial stenoses. Two theoretical models have been developed for deriving the reflection coefficient: a linear model resulting from the linearization of the pressure drop-flow equation and an ...