Knowledge translation (KT) is the activities involved in moving research from the laboratory, the research journal, and the academic conference into the hands of people and organizations who can put it to practical use. Knowledge translation is most often used in the health professions, including medicine, nursing, pharmaceuticals, rehabilitation, physical therapy, and public health. Depending on the type of research being translated, the "practical user" might be a medical doctor, a nurse, a teacher, a school administrator, an occupational or physical therapist, a legislator, an epidemiologist, a community health worker, or a parent. KT is not an action, but a spectrum of activities which will change according to the type of research, the time frame, and the audience being targeted. The most widely used definition of knowledge translation was published in 2000 by the Canadian Institutes of Health Research (CIHR): "Knowledge translation (KT) is defined as a dynamic and iterative process that includes synthesis, dissemination, exchange and ethically-sound application of knowledge to improve the health of Canadians, provide more effective health services and products and strengthen the health care system." Using the CIHR definition as a basis, the National Center for the Dissemination of Disability Research (NCDDR) published this definition of KT in 2005: "The collaborative and systematic review, assessment, identification, aggregation, and practical application of high-quality disability and rehabilitation research by key stakeholders (i.e., consumers, researchers, practitioners, and policymakers) for the purpose of improving the lives of individuals with disabilities." In 2006, Graham, et al., acknowledged the proliferation of related terms for the activity of knowledge translation, documenting 29 different terms used by 33 different health research funding agencies in their publications, including knowledge transfer, knowledge mobilization, knowledge exchange, implementation, and translational research.

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