Publications related to Neurotransmitter receptor

Theoretical analysis of divalent cation effects on aptamer recognition of neurotransmitter targets

Nako Nakatsuka, Dmitry Momotenko, Annina Stuber

Aptamer-based sensing of small molecules such as dopamine and serotonin in the brain, requires characterization of the specific aptamer sequences in solutions mimicking the in vivo environment with physiological ionic concentrations. In particular, divalen ...

2023

Rules and mechanisms governing G protein coupling selectivity of GPCRs

Bruno Emanuel Ferreira De Sousa Correia, Pablo Gainza Cirauqui

G protein-coupled receptors (GPCRs) convert extracellular stimuli into intracellular signaling by coupling to heterotrimeric G proteins of four classes: Gi/o, Gq, Gs, and G12/13. However, our understanding of the G protein selectivity of GPCRs is incomplet ...

Cambridge2023

A conditional glutamatergic synaptic vesicle marker for Drosophila

Evelyne Ruchti, Brian Donal McCabe

Glutamate is a principal neurotransmitter used extensively by the nervous systems of all vertebrate and invertebrate animals. It is primarily an excitatory neurotransmitter that has been implicated in nervous system development, as well as a myriad of brai ...

OXFORD UNIV PRESS INC2022

Aptamer-modified biosensors to visualize neurotransmitter flux

Nako Nakatsuka, Emilie Vuille-Dit-Bille

Chemical biosensors with the capacity to continuously monitor various neurotransmitter dynamics can be powerful tools to understand complex signaling pathways in the brain. However, in vivo detection of neurochemicals is challenging for many reasons such a ...

2022

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Thorsten Kleinjung, Patrick Karl Alois Neff

We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...

2022

Carl Petersen, Sylvain Crochet, Romain Guiet, Vahid Esmaeili, Yanqi Liu, Georgios Foustoukos, Keita Tamura, Anastasiia Oryshchuk, Reza Asri

Excitatory and inhibitory neurons in diverse cortical regions are likely to contribute differentially to the transformation of sensory information into goal-directed motor plans. Here, we investigate the relative changes across mouse sensorimotor cortex in ...

2022

Clathrin-associated AP-1 control stermination of STING signalling

Andrea Ablasser, Jonathan Jean-Pierre Ricci, Chong Liu, Pengbiao Xu, Ying Liu, Sophie Marie Elisabeth Rivara

Stimulator of interferon genes (STING) functions downstream of cyclic GMP-AMP synthase in DNA sensing or as a direct receptor for bacterial cyclic dinucleotides and small molecules to activate immunity during infection, cancer and immunotherapy(1-10). Prec ...

NATURE PORTFOLIO2022

Significance of Receptor Mobility in Multivalent Binding on Lipid Membranes

Maartje Martina Cornelia Bastings, Diana Kornelia Morzy

Numerous key biological processes rely on the concept of multivalency, where ligands achieve stable binding only upon engaging multiple receptors. These processes, like viral entry or immune synapse formation, occur on the diffusive cellular membrane. One ...

WILEY-V C H VERLAG GMBH2022

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Neurotransmitter receptor

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

Theoretical analysis of divalent cation effects on aptamer recognition of neurotransmitter targets

Rules and mechanisms governing G protein coupling selectivity of GPCRs

A conditional glutamatergic synaptic vesicle marker for Drosophila

Aptamer-modified biosensors to visualize neurotransmitter flux

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas

Clathrin-associated AP-1 control stermination of STING signalling

Significance of Receptor Mobility in Multivalent Binding on Lipid Membranes

A conditional GABAergic synaptic vesicle marker for Drosophila

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Chat with Graph Search

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

A conditional glutamatergic synaptic vesicle marker for Drosophila

Rules and mechanisms governing G protein coupling selectivity of GPCRs

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas

Theoretical analysis of divalent cation effects on aptamer recognition of neurotransmitter targets

Aptamer-modified biosensors to visualize neurotransmitter flux

Significance of Receptor Mobility in Multivalent Binding on Lipid Membranes

A conditional GABAergic synaptic vesicle marker for Drosophila

Clathrin-associated AP-1 control stermination of STING signalling