Concept

Head injury

Related publications (131)

Gait Control and Locomotor Recovery after Spinal Cord Injury

The gait of patients with an incomplete spinal cord injury (iSCI) has been studied previously. The most widely examined parameters to characterize iSCI gait are walking speed and time-distance measures (e.g., step length, step frequency, gait-cycle phases) ...

ETH Zurich2014

Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits

Jean-Philippe Thiran, David Paul Roger Romascano, Cristina Granziera, Djalel Eddine Meskaldji, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin, Gloria Menegaz

Conventional magnetic resonance imaging (MRI) of patients with multiple sclerosis provides only limited insights into the nature of brain tissue damage with modest clinical-radiological correlations. In this study, quantitative and semi-quantitative MRI te ...

2014

EMG-based pattern recognition approach in post stroke robot-aided rehabilitation: a feasibility study

Silvestro Micera

Background: Several studies investigating the use of electromyographic (EMG) signals in robot-based stroke neurorehabilitation to enhance functional recovery. Here we explored whether a classical EMG-based patterns recognition approach could be employed to ...

BioMed Central2013

Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury

Grégoire Courtine, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler, Janine Beauparlant

Severe spinal cord injury in humans leads to a progressive neuronal dysfunction in the chronic stage of the injury. This dysfunction is characterized by premature exhaustion of muscle activity during assisted locomotion, which is associated with the emerge ...

Oxford University Press2013

Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Tobias Kober, Reto Meuli, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Gunnar Krüger, Alexis Roche, François Lazeyras

Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Public Library of Science2013

Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury

Pierre Magistretti, Jocelyne Bloch, Reto Meuli

Growing evidence suggests that endogenous lactate is an important substrate for neurons. This study aimed to examine cerebral lactate metabolism and its relationship with brain perfusion in patients with severe traumatic brain injury (TBI). A prospective c ...

Nature Publishing Group2013

Motor execution detection based on autonomic nervous system responses

Roger Gassert, Olivier Lambercy, Martin Wolf, Marie-Christine Fluet, Raphaël Zimmermann

Triggered assistance has been shown to be a successful robotic strategy for provoking motor plasticity, probably because it requires neurologic patients’ active participation to initiate a movement involving their impaired limb. Triggered assistance, howev ...

2013

Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice

Nikolaos Stergiopoulos, Katia Galan, Luciano Dos Santos Aggum Capettini, Jean-Christophe Copin, Danielle Gomes Passos Silva

Neutrophilic inflammation might have a pathophysiological role in both carotid plaque rupture and ischemic stroke injury. Here, we investigated the potential benefits of the CXC chemokine-binding protein Evasin-3, which potently inhibits chemokine bioactiv ...

Nature Publishing Group2013

Investigation of field and diffusion time dependence of the diffusion-weighted signal at ultrahigh magnetic fields

Rolf Gruetter, Yohan Van de Looij, Nicolas Kunz

Over the last decade, there has been a significant increase in the number of high-magnetic-field MRI magnets. However, the exact effect of a high magnetic field strength (B0 ) on diffusion-weighted MR signals is not yet fully understood. The goal of this s ...

Wiley-Blackwell2013

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

Silvestro Micera, Grégoire Courtine, Eduardo Martin Moraud, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler, Simone Ellen Joze Duis, Isabel Laura Vollenweider, Kay Alexander Bartholdi

Half of human spinal cord injuries lead to chronic paralysis. Here, we introduce an electrochemical neuroprosthesis and a robotic postural interface designed to encourage supraspinally-mediated movements in rats with paralyzing lesions. Despite the interru ...

2012

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