Publications related to Virus latency

Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase

Neuraminidase (NA) inhibitors are used for the prevention and treatment of influenza A virus infections. Two subtypes of NA, N1 and N2, predominate in viruses that infect humans, but differential patterns of drug resistance have emerged in each subtype des ...

Amer Chemical Soc2016

Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b

Stewart Cole, Claudia Sala, Andrej Benjak, Ming Zhang, Jérémie Piton, Swapna Uplekar

Background: The ability of Mycobacterium tuberculosis to establish a latent infection (LTBI) in humans confounds the treatment of tuberculosis. Consequently, there is a need to discover new therapeutic agents that can kill M. tuberculosis both during activ ...

BioMed Central2016

Nucleoside Analogues: Synthesis from Strained Rings

Jérôme Waser, Jérémy Vuilleumier, Sophie Lucie Racine

Nucleoside analogues are widely employed as bioactive compounds against cancer and viral infections. Consequently, it is important to develop efficient synthetic methods to access them with high efficiency and structural diversity. Herein, we present a ful ...

Wiley-V C H Verlag Gmbh2016

Inside Job: Viruses Transfer cGAMP between Cells

Andrea Ablasser, Muhammet Fatih Gülen

The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. In a recent issue of Science, two studies, Bridgeman et al. (2015) and Gentili et al. (2015), report a novel mechanism for propagating an antiviral signal be ...

Cell Press2015

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

Didier Trono, Isabelle Barde, Adamantia Kapopoulou, Marco Cassano, Suk Min Jang, Benjamin Rauwel

Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can be fat ...

2015

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Jacques Fellay, Christian Axel Wandall Thorball, Amalio Telenti, Istvan Bartha, Julia di Iulio

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to pr ...

Public Library Science2014

Host miRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency

Jiri Vanicek

Reactivation of human cytomegalovirus (HCMV) is a significant cause of disease and death in immunocompromised patients underscoring the need to understand how latency is controlled. Here we demonstrate that HCMV has evolved to utilize cellular miRNAs in ce ...

American Society for Microbiology2014

How Viruses Hijack the ERAD Tuning Machinery

Maurizio Molinari, Riccardo Bernasconi

An essential step during the intracellular life cycle of many positive-strand RNA viruses is the rearrangement of host cell membranes to generate membrane-bound replication platforms. For example, Nidovirales and Flaviviridae subvert the membrane of the en ...

Amer Soc Microbiology2014

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Virus latency

No Evidence for Association of beta-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS

Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase

Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b

Nucleoside Analogues: Synthesis from Strained Rings

Methods for purging isolated organs and cells from latent human cytomegalovirus

Inside Job: Viruses Transfer cGAMP between Cells

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Host miRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency

How Viruses Hijack the ERAD Tuning Machinery

Graph Chatbot

Chat with Graph Search

Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b

Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase

Nucleoside Analogues: Synthesis from Strained Rings

No Evidence for Association of beta-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS

Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

Methods for purging isolated organs and cells from latent human cytomegalovirus

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

How Viruses Hijack the ERAD Tuning Machinery

Host miRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency

Inside Job: Viruses Transfer cGAMP between Cells