Publications related to Glucose-6-phosphate dehydrogenase deficiency

In vitro-transfusional model for red-blood-cell study: the advantage of lowering hematocrit

Gerardo Turcatti, David Crettaz, Michel Prudent, Manon Sandra Bardyn

Background - Thequalityof red blood cells (RBCs) stored in red cell concentrates (RCCs) is influenced by processing, storage and donor characteristics, and can have a clinical impact on transfused patients. To evaluate RBC properties and their potential im ...

Simtipro Srl2023

Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis

Kristina Schoonjans

Women with intrahepatic cholestasis of pregnancy (ICP), a disorder characterised by raised serum bile acids, are at increased risk of developing gestational diabetes mellitus and have impaired glucose tolerance whilst cholestatic. FXR and TGR5 are modulato ...

NATURE PUBLISHING GROUP2020

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Loïc Dayon, Andreas Wiederkehr, Sofia Moco, Isabelle Chareyron

Aims/hypothesis In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells durin ...

2020

Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

Rolf Gruetter, Hongxia Lei, Bernard Lanz, João Miguel das Neves Duarte, Antoine Timothée Cherix, Blanca Lizarbe Serra

PURPOSE: Determine the feasibility of (1) H-[(13) C] MRS in the mouse hypothalamus using a 14.1T magnet. METHODS: We optimized the design of a (1) H-[(13) C] surface coil to maximize the signal-to-noise ratio of (1) H-[(13) C] MRS in the mouse hypothalamus ...

2018

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

Rolf Gruetter, João Miguel das Neves Duarte, Kim Do, Alberto Corcoba

Environmental stress can interact with genetic predisposition to increase the risk of developing psychopathology. In this work, we tested the hypothesis that social isolation stress interacts with impaired glutathione synthesis and have cumulative effects ...

Wiley-Blackwell2017

De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria

Inmaculada Rentero Rebollo

Creative strategies for identifying new antibiotics are essential to addressing the looming threat of a post-antibiotic era. We here report the use of a targeted peptide phage display screen as a means of generating novel antimicrobial lipopeptides. Specif ...

Royal Soc Chemistry2017

Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks

Vassily Hatzimanikatis, Meriç Ataman, Stepan Tymoshenko, Dominique Soldati-Favre

Novel antimalarial therapies are urgently needed for the fight against drug-resistant para- sites. The metabolism of malaria parasites in infected cells is an attractive source of drug targets but is rather complex. Computational methods can handle this co ...

Public Library of Science2017

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Luciano Andres Abriata

The understanding of protein evolution depends on the ability to relate the impact of mutations on molecular traits to organismal fitness. Biological activity and robustness have been regarded as important features in shaping protein evolutionary landscape ...

Oxford Univ Press2016

Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 Tesla

Rolf Gruetter, Lijing Xin, Hongxia Lei, Bernard Lanz

(13)C magnetic resonance spectroscopy (MRS) combined with the administration of (13)C labeled substrates uniquely allows to measure metabolic fluxes in vivo in the brain of humans and rats. The extension to mouse models may provide exclusive prospect for t ...

Nature Publishing Group2015

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Glucose-6-phosphate dehydrogenase deficiency

In vitro-transfusional model for red-blood-cell study: the advantage of lowering hematocrit

Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria

Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks

Optimizing the extraction of extracellular DNA of aerobic granular biofilms

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 Tesla

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Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis

In vitro-transfusional model for red-blood-cell study: the advantage of lowering hematocrit

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks

Optimizing the extraction of extracellular DNA of aerobic granular biofilms

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria

Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 Tesla