Concept

Congenital vertebral anomaly

Related publications (31)

Closed-Loop Control of Epidural Electrical Stimulation in Patients with Spinal Cord Injury and Parkinson's Disease

Over the past two decades, epidural electrical stimulation (EES) has transitioned from a treatment for chronic pain to a promising paradigm for ameliorating deficits associated with neurological disorders like spinal cord injury (SCI) and Parkinson's Disea ...

EPFL2023

Reaction wavefront theory of notochord segment patterning

Andrew Charles Oates

The vertebrate axis is segmented into repetitive structures, the vertebrae. In fish, these segmented structures are thought to form from the paraxial mesoderm and the adjacent notochord. Recent work revealed an autonomous patterning mechanism in the zebraf ...

FRONTIERS MEDIA SA2022

Hunting for the wavefront: investigation of somite boundary positioning in zebrafish

Arianne Bercowsky Rama

Somitogenesis is the rhythmic and sequential formation of somites, which are tissue blocks that give rise to segmented adult body structures including the vertebrae and associated muscle. Somite formation is controlled by the segmentation clock, a populati ...

EPFL2022

Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders

Andreas Rowald

Spinal Cord Injury (SCI) disrupts the communication between the brain and spinal circuits below the lesion, leading to a plethora of neurological impairments, including the loss of motor function. At present, the only medical practices to enhance recovery ...

EPFL2021

Lumbar and thoracic kinematics during step-up: Comparison of three-dimensional angles between patients with chronic low back pain and asymptomatic individuals

Julien Favre, Guillaume Christe

While alterations in spinal kinematics have been repeatedly observed in patients with chronic low back pain (CLBP), their exact nature is still unknown. Specifically, there is a need for comprehensive assessments of multisegment spinal angles during daily- ...

2020

Refinements of hybrid neurophysical volume conductor models and application to study epidural electrical stimulation of the cervical spinal cord

Nathan Antoine Greiner

After spinal cord injury (SCI), the communication between the brain and spinal neural circuits below the lesion is disrupted, leading to paralysis. Epidural electrical stimulation (EES) of the lumbosacral spinal cord has been shown to restore locomotion an ...

EPFL2020

Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

Tobias Kober, Tom Hilbert, Michael Weber

Objectives This study evaluates GRAPPATINI, an accelerated T-2 mapping sequence combining undersampling and model-based reconstruction to facilitate the clinical implementation of T-2 mapping of the lumbar intervertebral disc. Methods Fifty-eight individua ...

SPRINGER2020

Spatiotemporal stimulation strategies in neuroprostheses to improve locomotion after spinal cord injury

Jérôme Gandar

Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of neurological disorders including paralysis. Current rehabilitation strategies to restore locomotion are poorly effective in people with severe SCI. Epidural ...

EPFL2019

Axon regeneration and circuit reorganization after complete spinal cord injury

Sabry Leonardo Barlatey

First human trials involving neuroprosthetic rehabilitation demonstrated recently that significant functional benefits can be achieved with lumbosacral neuromodulation and reorganized spared projections. However, complete spinal cord injuries (SCI) wholly ...

EPFL2019

A Computational Framework for the Design of Spinal Neuroprostheses

Silvestro Micera, Grégoire Courtine, Jocelyne Bloch, Marco Capogrosso

Severe Spinal Cord Injury (SCI) alters the communication between supra-spinal centers and the sensorimotor networks coordinating limb movements, which are usually located below the injury. Epidural electrical stimulation of lumbar segments has shown the ab ...

Springer International Publishing Ag2017

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.