Concept
Corneal dystrophy
Related publications (17)
Corneal epithelial stem cells and their niche at a glance
The corneal epitheliumacts as a protective barrier on the anterior ocular surface and is essential for maintaining transparency of the cornea and thus visual acuity. During both homeostasis and repair, the corneal epithelium is maintained by self-renewing ...
Company Of Biologists Ltd2017Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction
Freddy Radtke, Matthias Lütolf, Georg Fantner, Yann Barrandon, Sylke Höhnel, Pascal Damian Odermatt, Craig Nowell, Luca Azzolin
Chronic inflammation is associated with a variety of pathological conditions in epithelial tissues, including cancer, metaplasia and aberrant wound healing. In relation to this, a significant body of evidence suggests that aberration of epithelial stem and ...
Nature Publishing Group2016Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus
Keratoconus, a common inherited ocular disorder resulting in progressive corneal thinning, is the leading indication for corneal transplantation in the developed world. Genome-wide association studies have identified common SNPs 100 kb upstream of ZNF469 s ...
Oxford University Press2014