Concept

Weight loss

Related publications (132)

The role of nicotinamide riboside metabolism in pancreatic beta cells

Pancreatic beta cells play a major role in the regulation of glucose homeostasis by secreting insulin in response to elevated blood glucose levels. A gradual deterioration of functional beta cell mass and the chronic elevation of blood glucose levels are c ...

EPFL2022

The Price of Distributed: Rate Loss in the CEO Problem

Michael Christoph Gastpar, Alper Köse, Ahmet Arda Atalik

In the distributed remote (CEO) source coding problem, many separate encoders observe independently noisy copies of an underlying source. The rate loss is the difference between the rate required in this distributed setting and the rate that would be requi ...

2022

The progressive loss of brain network fingerprints in Amyotrophic Lateral Sclerosis predicts clinical impairment

Enrico Amico, Antonella Romano

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by functional connectivity alterations in both motor and extra-motor brain regions. Within the framework of network analysis, fingerprinting represents a reliable approach to ...

ELSEVIER SCI LTD2022

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Johan Auwerx, Maroun Bou Sleiman, Evan Graehl Williams, Pooja Jha

How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...

NATURE PORTFOLIO2021

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

Felix Naef, Nicholas Edward Phillips

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships ...

2021

Probing the Limits of Optical Loss in Ion-Sliced Thin-film Lithium Niobate

Tobias Kippenberg, Guanhao Huang, Mikhail Churaev, Junqiu Liu, Zelin Tan, Di Zhu

We measured the absorption-limited loss at telecommunication wavelengths for thin-film lithium niobate micro-ring resonators using Kerr-calibrated linear response technique. We find the average absorption loss-rate kappa(abs)/2 pi to be 3.65 +/- 0.70 MHz, ...

IEEE2021

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Mats Julius Stensrud, Aaron Leor Sarvet

Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...

2021

Conceptual design of 1000 m scale steel-UHPFRC composite truss arch bridge

Xiujiang Shen, Ping Zhu

Excessive self-weight and difficulty in construction are the main issues confronted by super-long-span arch bridges. To address these issues, a conceptual design of steel-ultra-high performance fibre-reinforced concrete (UHPFRC) composite truss arch bridge ...

ELSEVIER SCI LTD2021

Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity

Johan Auwerx, Kristina Schoonjans

Sirtuin 3 (SIRT3) is a protein deacetylase regulating beta-cell function through inhibiting oxidative stress in obese and diabetic mice, but the detailed mechanism and potential effect of beta-cell-specific SIRT3 on metabolic homeostasis, and its potential ...

AMER DIABETES ASSOC2021

The role and transcriptional regulation of FAM46A in adipocyte differentiation

Ann-Kristin Hov

Obesity is currently a leading global health concern. Treatments include undergoing a weight-loss regimen. However, successful weight-loss is variable, where the heritability of obesity is considered part of the cause. This patient variability to weight-lo ...

EPFL2021

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