Orofacial pain is a general term covering any pain which is felt in the mouth, jaws and the face. Orofacial pain is a common symptom, and there are many causes. Orofacial Pain (OFP) is the specialty of dentistry that encompasses the diagnosis, management and treatment of pain disorders of the jaw, mouth, face and associated regions. These disorders as they relate to orofacial pain include but are not limited to temporomandibular muscle and joint (TMJ) disorders, jaw movement disorders, neuropathic and neurovascular pain disorders, headache, and sleep disorders. International Classification of Diseases (ICD-11) is a new classification coming into effect as of January 1, 2022. It includes chronic secondary headaches and orofacial pain. The classification has been established by a close cooperation between International Association for the Study of Pain (IASP), World Health Organization (WHO) and the International Headache Society (IHS). There are 4 main classifications prior to ICD-11 which attempt to classify the causes of orofacial pain. The International Classification of Headache Disorders third edition (ICHD-3), a publication by the International Headache Society. The Classification of Chronic Pain Second Edition (Revised), a publication by the International Association for the Study of Pain. Orofacial Pain: Guidelines for Assessment, Diagnosis, and Management, Fifth Edition by American Academy of Orofacial Pain (AAOP): www.aaop.org. The Research Diagnostic Criteria for Temporomandibular Disorders (see TMD). It has also been suggested that the most basic etiologic classification of orofacial pain is into the following 3 groups: Primarily somatic, arising from musculoskeletal (e.g. TMD pain or periodontal pain) or visceral structures (e.g. pulpal pain or pain from the salivary glands), and transmitted via an intact pain transmission and modulation system. Primarily neuropathic, which occurs as a result of abnormal or damaged pain pathways, e.g. a surgical or traumatic injury to a peripheral nerve.