Publications related to Genetic diversity

Landscape Genomics: Understanding Relationships Between Environmental Heterogeneity and Genomic Characteristics of Populations

Stéphane Joost, Oliver Michele Selmoni

Landscape genomics is a rapidly advancing research field that combines population genomics, landscape ecology, and spatial analytical techniques to explicitly quantify the effects of environmental heterogeneity on neutral and adaptive genetic variation and ...

Springer2019

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

Jacques Fellay, Christian Hammer, Flavia Aurelia Shoko Hodel, Petar Scepanovic

Background The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu Interieur Consortium, a total ...

2019

Functional characterization of 3D protein structures informed by human genetic diversity

Amalio Telenti, Istvan Bartha, Julia di Iulio

Sequence variation data of the human proteome can be used to analyze 3D protein structures to derive functional insights. We used genetic variant data from nearly 140,000 individuals to analyze 3D positional conservation in 4,715 proteins and 3,951 homolog ...

PNAS2019

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

Jacques Fellay, Nimisha Chaturvedi

Genetic variation in the peptide-binding groove of the highly polymorphic HLA class I molecules has repeatedly been associated with HIV-1 control and progression to AIDS, accounting for up to 12% of the variation in HIV-1 set point viral load (spVL). This ...

NATL ACAD SCIENCES2019

Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress

Bart Deplancke, Virginie Sandra Braman, Maroun Bou Sleiman, Maria Litovchenko, Michael Vincent Frochaux

Eukaryotic genomes encode several buffering mechanisms that robustly maintain invariant phenotypic outcome despite fluctuating environmental conditions. Here we show that the Drosophila gut-associated commensals, represented by a single facultative symbion ...

2019

Benchmarking protocols for the metagenomic analysis of stream biofilm viromes

Tom Ian Battin, Hannes Markus Peter, Massimo Bourquin, Jade Brandani, Meriem Bekliz

Viruses drive microbial diversity, function and evolution and influence important biogeochemical cycles in aquatic ecosystems. Despite their relevance, we currently lack an understanding of their potential impacts on stream biofilm structure and function. ...

PeerJ2019

Methods of diagnosis alzheimer's disease

Johannes Gräff, Jose Vicente Sanchez Mut

A method for the diagnosis or prognosis of Alzheimer's disease (AD), includes the steps of placing a sample isolated from a person suspected of having AD onto a substrate labeling the sample to identify at least one epigenetic marker and/or genetic variati ...

2018

Contrasting responses of bacterial and fungal communities to plant litter diversity in a Mediterranean oak forest

Mathieu Raymond Santonja

Tree species diversity of forested ecosystems control the diversity of leaf litter inputs to the soil, with cascading effects on the microbial communities colonizing decomposing litter. However, the extent to which bacterial and fungal communities inhabiti ...

PERGAMON-ELSEVIER SCIENCE LTD2018

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Genetic diversity

Landscape Genomics: Understanding Relationships Between Environmental Heterogeneity and Genomic Characteristics of Populations

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

Genome-wide variation in nucleotides and retrotransposons in alpine populations of Arabis alpina (Brassicaceae)

Functional characterization of 3D protein structures informed by human genetic diversity

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress

Benchmarking protocols for the metagenomic analysis of stream biofilm viromes

Associations between genetic variations and global motion perception

Methods of diagnosis alzheimer's disease

Contrasting responses of bacterial and fungal communities to plant litter diversity in a Mediterranean oak forest

Graph Chatbot

Chat with Graph Search

Landscape Genomics: Understanding Relationships Between Environmental Heterogeneity and Genomic Characteristics of Populations

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

Functional characterization of 3D protein structures informed by human genetic diversity

Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress

Methods of diagnosis alzheimer's disease

Genome-wide variation in nucleotides and retrotransposons in alpine populations of Arabis alpina (Brassicaceae)

Benchmarking protocols for the metagenomic analysis of stream biofilm viromes

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

Associations between genetic variations and global motion perception

Contrasting responses of bacterial and fungal communities to plant litter diversity in a Mediterranean oak forest