Concept
Gene density
Related publications (9)
Inferring transcript phylogenies
Bernard Moret, Yann Christinat
Alternative splicing, an unknown mechanism 20 years ago, is now recognized as a major mechanism for proteome and transcriptome diversity, particularly in mammals - some researchers conjecture that up to 90% of human genes are alternatively spliced. Despite ...
IEEE Press2011Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals
Jacques Fellay, Patrick Descombes, Amalio Telenti
There is great interindividual variability in HIV-1 viral setpoint after seroconversion, some of which is known to be due to genetic differences among infected individuals. Here, our focus is on determining, genome-wide, the contribution of variable gene e ...
2010Comparative genomic and phylogeographic analysis of Mycobacterium leprae
Stewart Cole, Jacques Rougemont, Philippe Busso, Pushpendra Singh, Alexandre Gattiker
Reductive evolution and massive pseudogene formation have shaped the 3.31-Mb genome of Mycobacterium leprae, an unculturable obligate pathogen that causes leprosy in humans. The complete genome sequence of M. leprae strain Br4923 from Brazil was obtained b ...
2009