Publications related to Fibroblast growth factor

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

Cathrin Brisken, Melody Swartz, Witold Waldemar Kilarski, Csaba Ferenc László, Elena Menietti, Dania Al Labban

Stromal fibroblast senescence has been linked to ageing-associated cancer risk. However, density and proliferation of cancer-associated fibroblasts (CAFs) are frequently increased. Loss or downmodulation of the Notch effector CSL (also known as RBP-Jκ) in ...

Nature Publishing Group2015

Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

Jeffrey Alan Hubbell, Mikaël Martino, Priscilla Suhasna Maithili Briquez

Significance: Growth factors are very promising molecules for the treatment of skin wounds. However, their translation to clinical use has been seriously limited, facing issues related to safety and cost-effectiveness. These problems may derive from the fa ...

Mary Ann Liebert, Inc2015

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Diego Chiappe, Tamara Tanos

Mitogen-activated protein kinase (MAPK) pathways constitute key regulatory elements linking extracellular stimuli to nuclear gene expression. Immediate-early responsive genes (IEGs) of the activator protein 1 (AP-1) family, such as fos, achieve peak expres ...

Portland Press Ltd2015

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Paul Joseph Dyson, Christian Hartinger

The clinical development of anticancer metallodrugs is often hindered by the elusive nature of their molecular targets. To identify the molecular targets of an antimetastatic ruthenium organometallic complex based on 1,3,5-triaza-7-phosphaadamantane (RAPTA ...

2015

The Great Escape; the Hallmarks of Resistance to Antiangiogenic Therapy

Patrycja Nowak-Sliwinska

The concept of antiangiogenic therapy in cancer treatment has led to the approval of different agents, most of them targeting the well known vascular endothelial growth factor pathway. Despite promising results in preclinical studies, the efficacy of antia ...

Amer Soc Pharmacology Experimental Therapeutics2015

A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies

Francesco Piraino

The intricate process of wound healing involves activation of biological pathways that work in concert to regenerate a tissue microenvironment consisting of cells and external cellular matrix (ECM) with enzymes, cytokines, and growth factors. Distinct stag ...

Hindawi Publishing Corp2015

Cell-Instructive Microgels with Tailor-Made Physicochemical Properties

Matthias Lütolf, Simone Allazetta, Laura Kolb, Samantha Zerbib

A microfluidic in vitro cell encapsulation platform to systematically test the effects of microenvironmental parameters on cell fate in 3D is developed. Multiple cell types including fibroblasts, embryonic stem cells, and cancer cells are incorporated in e ...

Wiley-V C H Verlag Gmbh2015

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

Philippe Abdel Sayed, Ariane Kaeppeli

Infections are one of the most common complications in burn injuries. In severe burns, the wound surface is optimal for microbial proliferation as the exudate is a protein rich environment. Autograft and cultured grafts are the main treatments used nowaday ...

2015

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Fibroblast growth factor

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Engineered cell instructive matrices for fetal membrane healing

The Great Escape; the Hallmarks of Resistance to Antiangiogenic Therapy

A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies

Bio-engineered collagen-fibrin scaffolds for enhancing urological tissue regeneration

Cell-Instructive Microgels with Tailor-Made Physicochemical Properties

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

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Chat with Graph Search

Bio-engineered collagen-fibrin scaffolds for enhancing urological tissue regeneration

An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

Cell-Instructive Microgels with Tailor-Made Physicochemical Properties

A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies

The Great Escape; the Hallmarks of Resistance to Antiangiogenic Therapy

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

Engineered cell instructive matrices for fetal membrane healing