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Gain of Wnt signaling through beta-catenin has been ascribed a critical function in the stimulation of hematopoietic stem cell self-renewal, whereas loss of beta-catenin is reportedly dispensable for hematopoiesis. Here we have used conditional mouse genet ...
Alloesthesia is a rare clinical condition that corresponds to a spatial disorder of stimulus localization, in which patients experience a given stimulus on the side opposite to the side of stimulation. Whereas it has been mostly described for unisensory st ...
The white adipocyte is at the center of dysfunctional regulatory pathways in various pathophysiological processes, including obesity, diabetes, inflammation, and cancer. Here, we show that the oncogenic steroid receptor coactivator-3 (SRC-3) is a critical ...
The amygdala is a brain area which plays a decisive role in fear and anxiety. Since exposure to chronic stress can induce profound effects in emotion and cognition, plasticity in specific amygdaloid nuclei in response to prior stress has been hypothesized ...
Geographic Information Science methods and tools are likely to help to extract useful and so far unknown information from large spatially explicit genetic datasets to understand the distribution of diversity among and within sheep and goat breeds. Consider ...
Homologues of Gpi8p, Gaa1p, Gpi16p, Gpi17p, and Cdc91p are essential components of the GPI transamidase complex that adds glycosylphosphatidylinositols (GPIs 1) to newly synthesized proteins in the ER. In mammalian cells, these five subunits remain stably ...
This article describes methods used to evaluate mRNA expression patterns on microarrays and their application in circadian biology. With the intention of complementing rather than duplicating the existing literature, particular emphasis is placed on experi ...
The applications to dynamic sports for an accurate analysis of trajectories represent a new perspective for carrier phase-based GPS positioning. Introduced in competitive skiing, the GPS technique provide all the qualitative data for a complete analysis of ...
Exploratory search over a collection often requires users to iteratively apply a variety of strategies, such as searching for more general or more specific concepts in reaction to the information they encounter. Rich semantic models, such as WordNet, are p ...
Intrathymic T-cell maturation critically depends on the selective expansion of thymocytes expressing a functionally rearranged T-cell receptor (TCR) beta chain. In addition, TCR-independent signals also contribute to normal T-cell development. It is unclea ...
