Concept

Bacillus thuringiensis

Related publications (33)

Weakened [corrected] taste-LPS association during endotoxin tolerance

In naive individuals, the administration of bacterial lipopolysaccharide (LPS) provokes a rapid systemic increase in pro-inflammatory cytokines such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-6, inducing an acute phase response inc ...

Elsevier2007

Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila

Bruno Lemaitre

Pseudomonas entomophila is an entomopathogenic bacterium that, upon ingestion, kills Drosophila melanogaster as well as insects from different orders. The complete sequence of the 5.9-Mb genome was determined and compared to the sequenced genomes of four P ...

Nature Publishing Group2006

Selections for enzymatic catalysts

Christian Heinis, Dario Neri

A review on various methods for the selection of catalysts using phage display. The different approaches (selection of catalysts by binding and direct selections for catalytic activity) are presented. Metallo-beta -lactamase BCII from Bacillus cereus was u ...

CRC Press2005

Anthrax toxin: the long and winding road that leads to the kill

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

The past five years have led to a tremendous increase in our molecular understanding of the mode of action of the anthrax toxin, one of the two main virulence factors produced by Bacillus anthracis. The structures of each of the three components of the tox ...

Elsevier2005

Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

Cytolytic pore-forming toxins are important for the virulence of many disease-causing bacteria. How target cells molecularly respond to these toxins and whether or not they can mount a defense are poorly understood. By using microarrays, we demonstrate tha ...

2004

Water-Assisted Reaction Mechanism of Monozinc b-Lactamases

Ursula Röthlisberger, Matteo Dal Peraro, Paolo Carloni

Hybrid Car-Parrinello QM/MM calcns. are used to investigate the reaction mechanism of hydrolysis of a common b-lactam substrate (cefotaxime) by the monozinc b-lactamase from Bacillus cereus (BcII). The calcns. suggest a fundamental role for an active site ...

2004

Substrate binding to mononuclear metallo-beta-lactamase from Bacillus cereus

Matteo Dal Peraro

Structure and dynamics of substrate binding (cefotaxime) to the catalytic pocket of the mononuclear zinc-beta-lactamase from Bacillus cereus are investigated by molecular dynamics simulations. The calculations, which are based on the hydrogen-bond pattern ...

2004

Heat flux as an on-line indicator of metabolic activity in pilot scale bioreactor during the production of Bacillus thuringiensis var. galleriae-based biopesticides

Urs von Stockar, Ian William Marison

The effective biotechnol. process development depends on the system for monitoring the activity of the culture during cultivation. The feasibility of monitoring the metabolic flux during the cultivation of Bacillus thuringiensis var. galleriae (Btg) in pil ...

2002

Exploring hydrophobic sites in proteins with xenon or krypton

X-ray diffraction is used to study the binding of xenon and krypton to a variety of crystallised proteins: porcine pancreatic elastase; subtilisin Carlsberg from Bacillus licheniformis; cutinase from Fusarium solani; collagenase from Hypoderma lineatum; he ...

1998

Use of reaction calorimetry to monitor and control microbial cultures producing industrially relevant secondary metabolites

Urs von Stockar, Ian William Marison

Bench-scale heat flux calorimetry is applied to monitor complex microbial systems producing secondary metabolites and having a rheol. complex behavior. With such systems, biol. metabolic activity can only be measured accurately if calorimetry is improved b ...

1998

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