Concept

Crossover study

Related publications (15)

A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutralization Profile of Two Investigational Long-Acting Anti-SARS-CoV-2 Monoclonal Antibodies

Introduction: COVID-19 remains a significant risk for the immunocompromised given their lower responsiveness to vaccination or infection. Therefore, passive immunity through long-acting monoclonal antibodies (mAbs) offers a needed approach for pre-exposure ...

2024

Efficacy and safety of transcranial direct current stimulation to the ipsilesional motor cortex in subacute stroke (NETS): a multicenter, randomized, double-blind, placebo-controlled trial

Friedhelm Christoph Hummel

Background Each year, five million people are left disabled after stroke. Upper -extremity (UE) dysfunction is a leading problem. Neuroplasticity can be enhanced by non-invasive brain stimulation (NIBS) but evidence from large, randomized multicenter trial ...

Elsevier2024

A Unified Experiment Design Approach for Cyclic and Acyclic Causal Models

Negar Kiyavash, Ehsan Mokhtarian, Saber Salehkaleybar

We study experiment design for unique identification of the causal graph of a system where the graph may contain cycles. The presence of cycles in the structure introduces major challenges for experiment design as, unlike acyclic graphs, learning the skele ...

2022

Identification of Vaccine Effects When Exposure Status Is Unknown

Mats Julius Stensrud

Results from randomized controlled trials (RCTs) help determine vaccination strategies and related public health policies. However, defining and identifying estimands that can guide policies in infectious disease settings is difficult, even in an RCT. The ...

2021

A causal framework for classical statistical estimands in failure-time settings with competing events

Mats Julius Stensrud

In failure-time settings, a competing event is any event that makes it impossible for the event of interest to occur. For example, cardiovascular disease death is a competing event for prostate cancer death because an individual cannot die of prostate canc ...

2020

Short term exposure to fine particulate matter and hospital admission risks and costs in the Medicare population: time stratified, case crossover study

Yun Wang, Christine Choirat

OBJECTIVE To assess risks and costs of hospital admission associated with short term exposure to fine particulate matter with diameter less than 2.5 mu m (PM2.5) for 214 mutually exclusive disease groups. DESIGN Time stratified, case crossover analyses wit ...

BMJ2019

Rethinking Sustainability Towards a Regenerative Economy (RESTORE) within an Adaptive Neighbourhood Design

Silvia Coccolo, Emanuele Naboni

The current paper presents the activities carried out by a Working Group (WG2) within the frame of the COST ActionCA16114 ‘RESTORE: Rethinking Sustainability Towards a Regenerative Economy’. The content is divided into two parts: a brief overview of the on ...

School of Architecture The Chinese University of Hong Kong2018

Electrically Assisted Movement Therapy in Chronic Stroke Patients With Severe Upper Limb Paresis: A Pilot, Single-Blind, Randomized Crossover Study

José del Rocio Millán Ruiz, Silvio Ionta, Andrea Biasiucci, Andrea Maesani, Stephanie Clarke

Objective To evaluate the effects of electrically assisted movement therapy (EAMT) in which patients use functional electrical stimulation, modulated by a custom device controlled through the patient's unaffected hand, to produce or assist task-specific up ...

Elsevier2017

Virtual reality improves embodiment and neuropathic pain caused by spinal cord injury

Olaf Blanke, Roberta Ronchi, Marco Solcà, Estelle Palluel, Polona Pozeg

Objective: To investigate changes in body ownership and chronic neuropathic pain in patients with spinal cord injury (SCI) using multisensory own body illusions and virtual reality (VR). Methods: Twenty patients with SCI with paraplegia and 20 healthy cont ...

Lippincott Williams & Wilkins2017

The effect of manual lymphatic drainage on swelling and its consequences following total knee arthroplasty: a randomized controlles trial

Kamiar Aminian, Guillaume Christe

Objective: To evaluate the effects of manual lymphatic drainage (MLD) on knee swelling and the assumed consequences of swelling after total knee arthroplasty (TKA). Design: Randomized controlled trial. Setting: Primary care hospital. Participants: Two grou ...

Elsevier2016

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