Concept
Leukocoria
Related publications (5)
The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma
Paul Joseph Dyson, Irina Sinenko, Roland Christopher Turnell-Ritson
Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improv ...
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2023BIRO1, a Cell-Permeable BH3 Peptide, Promotes Mitochondrial Fragmentation and Death of Retinoblastoma Cells
Retinoblastoma is the most common pediatric intraocular neoplasm. While retinoblastoma development requires the inactivation of both alleles of the retinoblastoma tumor suppressor gene (RB1) in the developing retina, additional genomic changes are involved ...
Amer Assoc Cancer Research2015The Bcl-2/Bcl-XL inhibitor ABT-737 promotes death of retinoblastoma cancer cells
Purpose: Retinoblastoma is a malignant tumor that usually develops in early childhood. During retinoblastoma spreading, RB1 gene inactivation is followed by additional genomic modifications which progressively lead to resistance of tumor cells to death. Dr ...
Informa Healthcare2013Chiasmatic Infiltration Secondary to Late Malignant Transformation of Retinoma
Purpose: To report the lethal course of malignant transformation of retinoma in an adult. Methods: Case report. A 40-year-old patient presented with retinoma in his right eye and retinoblastoma in his left eye. Enucleation was recommended but refused and t ...
Informa Healthcare2012Modern cataract surgery for radiation-induced cataracts in retinoblastoma
Background Surgery of radiation-induced cataracts in children with retinoblastoma (RB) is a challenge as early intervention is weighted against the need to delay surgery until complete tumour control is obtained. This study analyses the safety and function ...
2011