2C-B (4-Bromo-2,5-dimethoxyphenethylamine) is a synthetic psychedelic drug of the 2C family, commonly used as a recreational drug. It was first synthesized by Alexander Shulgin in 1974. To date, there is limited scientific information about its pharmacological properties, where the substance has been classified as a stimulant, hallucinogen, entactogen, and empathogen. As a recreational drug, 2C-B is sold as a white powder sometimes pressed in tablets or gel caps. In Shulgin's book PiHKAL, the dosage range is listed as 12–24 mg. It is also referred to by a number of street names. The drug is usually taken orally, but can also be insufflated or vaporized. While being primarily a psychedelic it is also a mild entactogen. 2C-B was synthesized from 2,5-dimethoxybenzaldehyde by Alexander Shulgin in 1974. It first saw use among the psychiatric community as an aid during therapy. 2C-B was first sold commercially as a purported aphrodisiac under the trade name "Erox", which was manufactured by the German pharmaceutical company Drittewelle. For several years, it was available as tablets in Dutch smart shops under the name "Nexus" and "B-Dub". 2C-B first became popularized in the United States as a short-lived substitute for the street drug Ecstasy when MDMA became illegal in 1985. Many 2C-B users are young adults who attend raves. Though 2C-B is still used in the rave subculture, commonly mistaken for and/or sold as Ecstasy, its intentional use has become more common in the 2000s. Street prices range between 30 per tablet in the United States in 2011 when purchased in small quantities. The current street price in the Netherlands ranges between €3 and €5 per tablet. Larger retail purchases cost between 500 per gram. Wholesale purchases of 2C-B can lower the price (300 per gram in 2001, 100 on the darknet in 2020). A powder which has been dyed pink may be sold as "tucibi", "tuci", "tussi" or "pink cocaine". This is not synonymous with 2C-B and instead refers to a mixture of drugs with pink dye.
Pierre Vogel, Sandrine Gerber, Claudia Bello