Concept
Sulfolobus solfataricus
Related publications (12)
Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8
Meiotic processes are potentially dangerous to genome stability and could be disastrous if activated in proliferative cells. Here we show that two key meiosis-defining proteins, the topoisomerase Spo11 (which forms double-strand breaks) and the meiotic coh ...
NATURE RESEARCH2021Chromatin Proteomics to Study Epigenetics - Challenges and Opportunities
Regulation of gene expression is essential for the functioning of all eukaryotic organisms. Understanding gene expression regulation requires determining which proteins interact with regulatory elements in chromatin. MS-based analysis of chromatin has emer ...
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC2021Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor
Beat Fierz, Louise Catherine Bryan, Kristina Makasheva
Single-molecule measurements provide detailed mechanistic insights into molecular processes, for example in genome regulation where DNA access is controlled by nucleosomes and the chromatin machinery. However, real-time single-molecule observations of nucl ...
AMER CHEMICAL SOC2021Dispersal limitations and historical factors determine the biogeography of specialized terrestrial protists
Edward Mitchell, Luca Bragazza, Mariusz Lamentowicz, Enrique Lara, Bertrand Fournier
Recent studies show that soil eukaryotic diversity is immense and dominated by micro-organisms. However, it is unclear to what extent the processes that shape the distribution of diversity in plants and animals also apply to micro-organisms. Major diversif ...
WILEY2019Comparing the anti-bacterial performance of chlorination and electrolysis post-treatments in a hand washing water recycling system
Innovative solutions are necessary to enable the decentralized recycling of greywater for applications requiring high-quality water, such as hand washing. While physical barriers such as ultrafiltration membranes effectively prevent the passage of bacteria ...
ELSEVIER SCIENCE BV2019The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase
Paolo De Los Rios, Pierre Goloubinoff
Hsp70-Hsp40-NEF and possibly Hsp100 are the only known molecular chaperones that can use the energy of ATP to convert stably pre-aggregated polypeptides into natively refolded proteins. However, the kinetic parameters and ATP costs have remained elusive be ...
Nature Publishing Group2010