Publications related to Cilium

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Meltem Weger

The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic development. We showed that knockdown of mond ...

2020

Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

Davide Demurtas, Georgios Hatzopoulos, Sergey Nazarov, Alexandra Bezler, Paul Guichard, Veronika Nemcíková Villímová

Centrioles are polarized microtubule-based organelles that seed the formation of cilia, and which assemble from a cartwheel containing stacked ring oligomers ofSAS-6 proteins. A cryo-tomography map of centrioles from the termite flagellateTrichonymphaspp. ...

2020

A biphasic growth model for cell pole elongation in mycobacteria

Georg Fantner, John McKinney, Haig Alexander Eskandarian, Mélanie Thérèse Marie Hannebelle, Chiara Toniolo, Joëlle Xiao Yuan Ven, Gaëlle Madeleine Vuaridel

Mycobacteria grow by inserting new cell wall material in discrete zones at the cell poles. This pattern implies that polar growth zones must be assembled de novo at each division, but the mechanisms that control the initiation of new pole growth are unknow ...

2020

Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging

Anders Meibom, Stéphane Laurent Escrig, Stéphanie Kéren Cohen

Extracellular bacterial symbionts communicate biochemically with their hosts to establish niches that foster the partnership. Using quantitative ion microprobe isotopic imaging (nanoscale secondary ion mass spectrometry [NanoSIMS]), we surveyed localizatio ...

WILEY2020

Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases

Daniel Constam, Benjamin Marcel Daniel Rothé, Céline Gagnieux, Lucía Carolina Leal Esteban

Polycystic kidneys frequently associate with mutations in individual components of cilia, basal bodies or centriolar satellites that perturb complex protein networks. In this review, we focus on the RNA-binding protein Bicaudal-C1 (BICC1) which was found m ...

2020

Single yeast cell nanomotions correlate with cellular activity

Giovanni Dietler, Sandor Kasas, María Inés Villalba, Anton Malovichko

Living single yeast cells show a specific cellular motion at the nanometer scale with a magnitude that is proportional to the cellular activity of the cell. We characterized this cellular nanomotion pattern of nonattached single yeast cells using classical ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Mechanomicrobiology: how bacteria sense and respond to forces

Alexandre Louis André Persat

Microbiology and biophysics are converging to advance our understanding of the mechanobiology of microorganisms. In this Review, Dufrene and Persat discuss the physical forces that bacteria experience in their natural environments and the structures that t ...

NATURE PUBLISHING GROUP2020

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

Anne-Florence Raphaëlle Bitbol

While the biofilm growth mode conveys notable thriving advantages to bacterial populations, the mechanisms of biofilm formation are still strongly debated. Here, we investigate the remarkable spontaneous formation of regular spatial patterns during the gro ...

Royal Society of Chemistry (RSC)2020

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

Davide Demurtas, Paul Guichard, Virginie Hamel

Microtubule doublets (MTDs), consisting of an incomplete B-microtubule at the surface of a complete A-microtubule, provide a structural scaffold mediating intraflagellar transport and ciliary beating. Despite the fundamental role of MTDs, the molecular mec ...

AMER ASSOC ADVANCEMENT SCIENCE2019

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Cilium

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

A biphasic growth model for cell pole elongation in mycobacteria

Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging

Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases

Single yeast cell nanomotions correlate with cellular activity

Mechanomicrobiology: how bacteria sense and respond to forces

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

Microbial life in porous systems

Graph Chatbot

Chat with Graph Search

Role of the RNA-binding protein Bicaudal-C1 and interacting factors in cystic kidney diseases

Single yeast cell nanomotions correlate with cellular activity

A biphasic growth model for cell pole elongation in mycobacteria

Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging

Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly

Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

Microbial life in porous systems

Mechanomicrobiology: how bacteria sense and respond to forces

Spatiotemporal pattern formation in E. coli biofilms explained by a simple physical energy balance