Concept
Acute myeloid leukemia
Related publications (114)
Deconvolution of ex-vivo drug screening data and bulk tissue expression predicts the abundance and viability of cancer cell subpopulations
Ex-vivo drug sensitivity screening (DSS) allows the prediction of cancer treatment effectiveness in a personalized fashion. However, it only provides a readout on mixtures of cells, potentially occulting important information on clinically relevant cell su ...
EPFL2024Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease
Acute leukemia has a high mortality rate of approximately 50%, and current methods are not effective in predicting disease progression and relapse. To improve our understanding of hematopoiesis and develop new markers for predicting disease relapse in dead ...
EPFL2023Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells
Cyrus Kazemiraad, Saeed Mohammadi
Vimentin is a main type 3 intermediate filament protein. It seems that abnormal expression of vimentin is contributed to the appearance of the aggressive feature of cancer cells. So that it has been reported that malignancy and epithelial-mesenchymal trans ...
SPRINGER2023Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling
Andéol Geoffroy Cadic-Melchior
Stroke is the main source of long-lasting disability, affecting dominantly motor functions. The extent and course of recovery are highly heterogeneous between patients, with a minority of patients fully recovering from their initial impairments, leaving 85 ...
EPFL2023The pro-apoptotic properties of a phytonutrient rich infusion of A. cherimola leaf extract on AML cells
Natalia Gasilova, Laure Menin, Rita Sarkis, Maria Younes
Annonaceae family has broad uses in herbal medicine for treatment of several diseases, whether through seeds' or leaves' extracts. The present study investigates the antiproliferative and antitumor activity of Annona cherimola aqueous leaf (AAL) extract/in ...
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER2021