Concept

Protein–protein interaction prediction

Related people (33)
John Richard Thome
John R. Thome is Professor of Heat and Mass Transfer at the Swiss Federal Institute of Technology in Lausanne (EPFL), Switzerland since 1998, where his primary interests of research are two-phase flow and heat transfer, covering both macro-scale and micro-scale heat transfer and enhanced heat transfer. He directs the Laboratory of Heat and Mass Transfer (LTCM) at the EPFL with a research staff of about 18-20 and is also Director of the Doctoral School in Energy. He received his Ph.D. at Oxford University, England in 1978. He is the author of four books: Enhanced Boiling Heat Transfer (1990), Convective Boiling and Condensation, 3rd Edition (1994), Wolverine Engineering Databook III (2004) and Nucleate Boiling on Micro-Structured Surfaces (2008). He received the ASME Heat Transfer Division's Best Paper Award in 1998 for a 3-part paper on two-phase flow and flow boiling heat transfer published in the Journal of Heat Transfer. He has received the J&E Hall Gold Medal from the U.K. Institute of Refrigeration in February, 2008 for his extensive research contributions on refrigeration heat transfer and more recently the 2010 ASME Heat Transfer Memorial Award. He has published widely on the fundamental aspects of microscale and macroscale two-phase flow and heat transfer and on enhanced boiling and condensation heat transfer.
Bruno Emanuel Ferreira De Sousa Correia
Throughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Vassily Hatzimanikatis
Dr. Vassily Hatzimanikatis is currently Associate Professor of Chemical Engineering and Bioengineering at Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. Vassily received a PhD and an MS in Chemical Engineering from the California Institute of Technology, and his Diploma in Chemical Engineering from the University of Patras, in Greece. After the completion of his doctoral studies, he held a research group leader position at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Prior to joining EPFL, Vassily worked for three years in DuPont, Cargill, and Cargill Dow, and he has been assistant professor at Northwestern University, at Illinois, USA. Vassily’s research interests are in the areas of computational systems biology, biotechnology, and complexity. He is associate editor of the journals Biotechnology & Bioengineering, Metabolic Engineering and Integrative Biology, and he serves on the editorial advisory board of the journals Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology, and Industrial Biotechnology. He has written over 70 technical publications and he is co-inventor in three patents and patent applications. Vassily is a fellow of the American Institute for Medical and Biological Engineering (2010), he was a DuPont Young Professor (2001-2004), and he has also received the Jay Bailey Young Investigator Award in Metabolic Engineering (2000), and the ACS Elmar Gaden Award (2011).
Horst Vogel
Horst Vogel est né en 1948 à Würzburg, Allemagne. Après ses études en chimie, il obtient le diplôme de chimie en 1974 de l'Université de Würzburg.Il entreprend ensuite un travail de doctorat au Max-Planck Institut für Biophysikalische Chemie de Göttingen, et obtient en 1978 le grade de docteur ès sciences de l'Université de Göttingen. De 1978 à 1983 il effectue des recherches au Max-Planck Institut für Biologie à Tübingen et en 1984, il rejoint le Biocentre à Bâle où il travaille jusqu'en 1989, effectuant une année au Karolinska Institute à Stockholm. En 1989, Horst Vogel rejoint l'institut de chimie physique de l'EPFL où il dirige un groupe travaillant dans les domaines de la biophysique et de la bioélectronique. Depuis le 1er octobre 1994 il est profeseur en chimie physique des polymères et membranes au Département de chimie de EPFL. Ses intérêts de recherche sont l'étude de la structure et de la dynamique de récepteurs membranaires et l'auto-assemblage des biomolécules aux interfaces pour développer de nouveaux biocapteurs dans le domaine de micro- et nanotechnologie. Il enseigne les sciences du vivant, la biophysique et biochimie, et des chapitres concernant la biotechnologie. Dipl. in Chemistry1974-Univ. Würzburg, DE Ph.D.-1978-MPI für Biophys. Chemie, Göttingen, DE
François Avellan
Prof. François Avellan, director of the EPFL Laboratory for Hydraulic Machines, graduated in Hydraulic Engineering from Ecole nationale supérieure d'hydraulique, Institut national polytechnique de Grenoble, France, in 1977 and, in 1980, got his doctoral degree in engineering from University of Aix-Marseille II, France. Research associate at EPFL in 1980, he is director of the EPFL Laboratory for Hydraulic Machines since 1994 and, in 2003, was appointed Ordinary Professor in Hydraulic Machinery. Supervising 37 EPFL doctoral theses, he was distinguished by SHF, Société hydrotechnique de France, awarding him the "Grand Prix 2010 de l'hydrotechnique". His main research domains of interests are hydrodynamics of turbine, pump and pump-turbines including cavitation, hydro-acoustics, design, performance and operation assessments of hydraulic machines. Prof. Avellan was Chairman of the IAHR Section on Hydraulic Machinery and Systems from 2002 to 2012. He has conducted successfully several Swiss and international collaborative research projects, involving key hydropower operators and suppliers, such as:
  • Coordination for the FP7 European project n° 608532 "HYPERBOLE: HYdropower plants PERformance and flexiBle Operation towards Lean integration of new renewable Energies" (2013-2017);
  • Deputy Head of the Swiss Competence Center for Energy Research – Supply of Electricity (SCCER-SoE) to carry out innovative and sustainable research in the areas of geo-energy and hydropower for phase I (2013-2016) and Phase II (2017, 2010) to be approved.
  • EUREKA European research projects: N° 4150 and N° 3246, "HYDRODYNA, Harnessing the dynamic behavior of pump-turbines", (2003-2011), N° 1605, "FLINDT, Flow Investigation in Draft Tubes", http://flindt.epfl.ch/, (1997-2002). N° 2418, "SCAPIN, Stability of Operation of Francis turbines, prediction and modeling";
  • Swiss KTI/CTI research projects with GE Renewable Energy (anc. ALSTOM Hydro), Birr, ANDRITZ Hydro, Kriens, FMV, Sion, Groupe E, Granges-Paccot, Power Vision engineering, Ecublens and SULZER Pumps, Winterthur.
  • ETH Domain, HYDRONET Project for the Competence Center Energy and Mobility, PSI Villingen.
Furthermore, he is involved in scientific expertise and independent contractual experimental validations of turbines and pump turbines performances for the main hydropower plants in the world. In recognition for his work as Convenor of the TC4 working group of experts in editing the IEC 60193 standard he received the "IEC 1906 Award" from the International Electrotechnical Commission.
Alexandre Massoud Alahi
Alexandre Alahi is currently an Assistant Professor at EPFL. He spent five years at Stanford University as a Post-doc and Research Scientist after obtaining his Ph.D. from EPFL. His research enables machines to perceive the world and make decisions in the context of transportation problems and smart environments. He has worked on the theoretical challenges and practical applications of socially-aware Artificial Intelligence, i.e., systems equipped with perception and social intelligence. He was awarded the Swiss NSF early and advanced researcher grants for his work on predicting human social behavior. He won the CVPR Open Source Award (2012) for his work on Retina-inspired image descriptors, and the ICDSC Challenge Prize (2009) for his sparsity-driven algorithm that has tracked more than 100 million pedestrians to date. His research has been covered internationally by BBC, abc, PBS, Euronews, Wall street journal, and other national news outlets around the world. Alexandre has also co-founded multiple startups such as Visiosafe, and won several startup competitions. He was elected as one of the Top 20 Swiss Venture leaders in 2010.

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