Concept
Leprosy
Related publications (82)
Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosis
Stewart Cole, Charlotte Avanzi, Thyago Leal Calvo
Author summaryLeprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae, an obligate intracellular bacterium. Diagnosis of leprosy often relies on skin examinations for clinical signs, bacilli staining from skin smears and invasive s ...
PUBLIC LIBRARY SCIENCE2022A new paradigm for leprosy diagnosis based on host gene expression
Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Thyago Leal Calvo
Author summary Despite effective treatment, leprosy is still a significant public health issue in more than 120 countries, with more than 200 000 new cases yearly. The disease is caused mainly by Mycobacterium leprae, a slow-growing bacillus still uncultiv ...
PUBLIC LIBRARY SCIENCE2021Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the Comoros
Stewart Cole, Andrej Benjak, Charlotte Avanzi, Philippe Busso, Pushpendra Singh, Thyago Leal Calvo
Human settlement of Madagascar traces back to the beginning of the first millennium with the arrival of Austronesians from Southeast Asia, followed by migrations from Africa and the Middle East. Remains of these different cultural, genetic, and linguistic ...
2020