Publications related to Cognitive reserve

Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer's Disease continuum?

Silvestro Micera, Michael Lassi

Alzheimer's disease (AD) pathological changes may begin up to decades earlier than the appearance of the first symptoms of cognitive decline. Subjective cognitive decline (SCD) could be the first pre-clinical sign of possible AD, which might be followed by ...

ELSEVIER SCI LTD2023

Lactate supply overtakes glucose when neural computational and cognitive loads scale up

Pierre Magistretti

Neural computational power is determined by neuroenergetics, but how and which energy substrates are allocated to various forms of memory engram is unclear. To solve this question, we asked whether neuronal fueling by glucose or lactate scales differently ...

NATL ACAD SCIENCES2022

Altered developmental trajectories of verbal learning skills in 22q11.2DS: associations with hippocampal development and psychosis

Maude Schneider, Karin Bortolin

Background The cognitive profile in 22q11.2 deletion syndrome (22q11.2DS) is often characterized by a discrepancy between nonverbal vs. verbal reasoning skills, in favor of the latter skills. This dissociation has also been observed in memory, with verbal ...

CAMBRIDGE UNIV PRESS2022

FORMINg a link between PTSD and AD

Johannes Gräff

Epidemiological evidence suggests that people suffering from post-traumatic stress disorder have a higher risk for developing Alzheimer's disease. The underlying mechanisms, however, remained thus far unexplored. In this issue of The EMBO Journal, Agis-Bal ...

Nature Publishing Group2017

Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

Silvestro Micera, Giovanni D'Angelo, Martina Coscia, Marco Mainardi

Age-related cognitive impairment and dementia are an increasing societal burden. Epidemiological studies indicate that lifestyle factors, e.g. physical, cognitive and social activities, correlate with reduced dementia risk; moreover, positive effects on co ...

Nature Publishing Group2017

Apathy and noradrenaline: silent partners to mild cognitive impairment in Parkinson's disease?

Kerstin Preuschoff, Leyla Loued-Khenissi

Purpose of review Mild cognitive impairment (MCI) is a comorbid factor in Parkinson's disease. The aim of this review is to examine the recent neuroimaging findings in the search for Parkinson's disease MCI (PD-MCI) biomarkers to gain insight on whether MC ...

Lippincott, Williams & Wilkins2015

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity

Liliane Glauser, Elpida Tsika, Darren Moore, Sarah Catherine Sonnay, Klodjan Stafa, Alzbeta Trancikova, David Ramonet Jimenez, Agata Podhajska

Mutations in the ATP13A2 gene (PARK9, OMIM 610513) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome and early-onset parkinsonism. ATP13A2 is an uncharacterized protein belonging to the P-5-type ATPase subfamily that is predicted to regulate t ...

Oxford University Press2012

Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

Darren Moore

There is emerging evidence implicating a role for the autophagy-ysosome pathway in the pathogenesis of Lewy body disease. We investigated potential neuropathologic and biochemical alterations of autophagy-lysosome pathway-related proteins in the brains of ...

Lippincott, Williams & Wilkins2011

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Cognitive reserve

Theta oscillations and minor hallucinations in Parkinson’s disease reveal decrease in frontal lobe functions and later cognitive decline

Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer's Disease continuum?

Lactate supply overtakes glucose when neural computational and cognitive loads scale up

Altered developmental trajectories of verbal learning skills in 22q11.2DS: associations with hippocampal development and psychosis

FORMINg a link between PTSD and AD

Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

Apathy and noradrenaline: silent partners to mild cognitive impairment in Parkinson's disease?

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity

Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

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Chat with Graph Search

Altered developmental trajectories of verbal learning skills in 22q11.2DS: associations with hippocampal development and psychosis

Theta oscillations and minor hallucinations in Parkinson’s disease reveal decrease in frontal lobe functions and later cognitive decline

Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer's Disease continuum?

Endogenous Regulators of Gamma-Secretase and Amyloid-Beta Production, and Engineering of Alzheimer's Disease Therapeutic Tools

FORMINg a link between PTSD and AD

Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity

Apathy and noradrenaline: silent partners to mild cognitive impairment in Parkinson's disease?

Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

Lactate supply overtakes glucose when neural computational and cognitive loads scale up