Publications related to Microbiome

Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans

Deregulated energy homeostasis represents a hallmark of aging and results from complex gene-by-environment interactions. Here, we discovered that reducing the expression of the gene ech-6 encoding enoyl-CoA hydratase remitted fat diet-induced deleterious e ...

NATURE PORTFOLIO2022

Growth and persistence of an aerobic microbial community in Wyoming bentonite MX-80 despite anoxic in-situ conditions

Rizlan Bernier-Latmani, Manon Frutschi, Niels Burzan, Roberta Murad Lima

Microbial activity has the potential to enhance the corrosion of high-level radioactive waste disposal canisters, which, in the proposed Swiss deep geological repository, will be embedded in bentonite and placed in the Opalinus Clay rock formation (OPA). T ...

2022

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

Henning Paul-Julius Stahlberg, Zhiva Skachokova

Abnormal tau protein aggregates constitute a hallmark of Alzheimer's disease. The mechanisms underlying the initiation of tau aggregation in sporadic neurodegeneration remain unclear. Here we investigate whether a non-human prion can seed tau aggregation. ...

2022

Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater

Rizlan Bernier-Latmani, Emma Bell

While oligotrophic deep groundwaters host active microbes attuned to the low-end of the bioenergetics spectrum, the ecological constraints on microbial niches in these ecosystems and their consequences for microbiome convergence are unknown. Here, we provi ...

NATURE RESEARCH2021

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

Mojgan Masoodi, Christopher Clark

Background Multiple pathophysiological processes have been described in Alzheimer's disease (AD). Their inter-individual variations, complex interrelations, and relevance for clinical manifestation and disease progression remain poorly understood. We hypot ...

BMC2021

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Anders Meibom, Guilhem Maurice Louis Banc-Prandi, Maoz Fine, Romain Savary

Corals from the northern Red Sea and Gulf of Aqaba exhibit extreme thermal tolerance. To examine the underlying gene expression dynamics, we exposed Stylophora pistillata from the Gulf of Aqaba to short-term (hours) and long-term (weeks) heat stress with p ...

2021

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Xavier Fernandez-Real Girona

Background Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. Methods We studied gut microbiome composition and ...

BMJ PUBLISHING GROUP2021

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities

Vassily Hatzimanikatis, Liliana Angeles Martinez

The metabolic capabilities of the species and the local environment shape the microbial interactions in a community either through the exchange of metabolic products or the competition for the resources. Cells are often arranged in close proximity to each ...

PUBLIC LIBRARY SCIENCE2021

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Microbiome

Multidisciplinary Investigation of the Gut-Brain Ecosystem in a Model of Alzheimer's Disease

Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans

Growth and persistence of an aerobic microbial community in Wyoming bentonite MX-80 despite anoxic in-situ conditions

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater

Thermal Stress Interacts With Surgeonfish Feces to Increase Coral Susceptibility to Dysbiosis and Reduce Tissue Regeneration

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities

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Chat with Graph Search

Multidisciplinary Investigation of the Gut-Brain Ecosystem in a Model of Alzheimer's Disease

Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater

Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans

Growth and persistence of an aerobic microbial community in Wyoming bentonite MX-80 despite anoxic in-situ conditions

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease

Thermal Stress Interacts With Surgeonfish Feces to Increase Coral Susceptibility to Dysbiosis and Reduce Tissue Regeneration

Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities