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Cardiomyocyte cultures exhibit spontaneous electrical and contractile activity, as in a natural cardiac pacemaker. In such preparations, beat rate variability exhibits features similar to those of heart rate variability in vivo. Mechanical deformations and ...
Continuous and reliable cardiac function monitoring could improve medication adherence in patients at risk of heart failure. This work presents an innovative implantable Fiber Bragg Grating-based soft sensor designed to sense mechanical cardiac activity. T ...
Mobile health is gradually taking more importance in our society and the need of new power efficient devices acquiring biosignals for long periods of time is becoming substantial. In this thesis, we study the power reduction we could achieve on ECG sensing ...
In rat mesenteric arteries, smooth muscle cells exhibit intercellular calcium waves in response to local phenylephrine stimulation. These waves have a velocity of similar to 20 cells/s and a range of similar to 80 cells. We analyze these waves in a theoret ...
Periodic environments like we experience on the surface of planet earth lead living organisms to evolve molecular anticipation devices known a circadian clocks. The word circadian refers to the period of these oscillations which last about (circa) one day ...
With the emergence of wearable and non-intrusive med- ical devices, one major challenge is the real-time analysis of the acquired signals in real-life and ambulatory con- ditions. This paper presents a lightweight algorithm for on-line heart beat classific ...
Atrial fibrillation is the most common sustained cardiac rhythm disturbance, increasing in prevalence with age. During the past 20 years, there has been a 66% increase in hospital admissions related to atrial fibrillation. Neither the natural history of at ...
Background In the literature, several different transfer matrices have been presented for deriving the vectorcardiogram (VCG) from the signals observed using a limited set of electrodes. Even when the electrode locations were identical, like 9 of the stand ...
Aims: Experimental models have reported conflicting results regarding the role of dispersion of repolarization in promoting atrial fibrillation (AF). Repolarization alternans, a beat-to-beat alternation in action potential duration, enhances dispersion of ...