Publications related to Childhood obesity

White adipose tissue distribution and amount are associated with increased white matter connectivity

Jean-Philippe Thiran, Gabriel Girard, Elda Fischi Gomez, Philipp Johannes Koch, Liana Okudzhava

Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...

Hoboken2024

Grape polyphenols decrease circulating branched chain amino acids in overfed adults

Jörg Hager, José Luis Abelleira Fernández, Sofia Moco

Introduction and aimsDietary polyphenols have long been associated with health benefits, including the prevention of obesity and related chronic diseases. Overfeeding was shown to rapidly induce weight gain and fat mass, associated with mild insulin resist ...

FRONTIERS MEDIA SA2022

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Xavier Fernandez-Real Girona

Background Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. Methods We studied gut microbiome composition and ...

BMJ PUBLISHING GROUP2021

Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

Kristina Schoonjans, Alessia Perino

Bile acids (BAs) improve metabolism and exert anti-obesity effects through the activation of the Takeda G protein-coupled receptor 5 (TGR5) in peripheral tissues. TGR5 is also found in the brain hypothalamus, but whether hypothalamic BA signaling is implic ...

CELL PRESS2021

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Mats Julius Stensrud, Aaron Leor Sarvet

Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...

2021

Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids

Xavier Fernandez-Real Girona

The gut microbiome has been linked to fear extinction learning in animal models. Here, we aimed to explore the gut microbiome and memory domains according to obesity status. A specific microbiome profile associated with short-term memory, working memory, a ...

CELL PRESS2020

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Johan Auwerx, Richardus Houtkooper

Background: Nicotinamide riboside (NR) is an NAD(+) precursor that boosts cellular NAD(+) concentrations. Preclinical studies have shown profound metabolic health effects after NR supplementation. Objectives: We aimed to investigate the effects of 6 wk NR ...

OXFORD UNIV PRESS2020

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Jacques Fellay, Christian Axel Wandall Thorball, Monia Guidi, Christian Hammer, Thierry Buclin

Objective. There is limited data on abdominal obesity and the influence of genetics on weight change after ant iretroviral therapy (ART) initiation. We assessed body mass index (BMI) and waist hip ration (WHR) change over time in the Swiss HIV Cohort study ...

OXFORD UNIV PRESS INC2020

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Childhood obesity

White adipose tissue distribution and amount are associated with increased white matter connectivity

Grape polyphenols decrease circulating branched chain amino acids in overfed adults

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mouse

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Asperuloside Improves Obesity and Type 2 Diabetes through Modulation of Gut Microbiota and Metabolic Signaling

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White adipose tissue distribution and amount are associated with increased white matter connectivity

Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways

Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

Grape polyphenols decrease circulating branched chain amino acids in overfed adults

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mouse

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Asperuloside Improves Obesity and Type 2 Diabetes through Modulation of Gut Microbiota and Metabolic Signaling