Related publications (8)

A Simple, Fast and Low-Cost Method for in situ Monitoring of Topographical Changes and Wear Rate of a Complex Tribo-System Under Mixed Lubrication

Daniel Sage, Bastian Meylan

This contribution presents a simple, fast, and low-cost method to track in situ and in real time the evolution of the surface topography. The method combines an optical method (collimated light) with image analysis. The method was validated using a complex ...
Elsevier2016

Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus

Keratoconus, a common inherited ocular disorder resulting in progressive corneal thinning, is the leading indication for corneal transplantation in the developed world. Genome-wide association studies have identified common SNPs 100 kb upstream of ZNF469 s ...
Oxford University Press2014

Modeling the cornea: an architectural approach

Julien Graber

Nowadays the mechanism regulating the corneal epithelium renewal still remains unclear. Until now it was thought to be the fact of stem cells distributed in the limbus, generating TA cells migrating towards the central cornea and responsible for its renewa ...
2009

Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells

Yann Barrandon

Hes1, a major target gene in Notch signaling, regulates the fate and differentiation of various cell types in many developmental systems. To gain a novel insight into the role of Hes1 in corneal tissue, we performed gain-of-function and loss-of-function st ...
2008

Oligopotent stem cells are distributed throughout the mammalian ocular surface

Yann Barrandon, Ariane Rochat, Georges Abou Jaoudé

The integrity of the cornea, the most anterior part of the eye, is indispensable for vision. Forty- five million individuals worldwide are bilaterally blind and another 135 million have severely impaired vision in both eyes because of loss of corneal trans ...
2008

Microfabricated thin film strain gage sensor with telemetry microprocessor embedded in a soft contact lens for minimally invasive intraocular pressure monitoring

Matteo Leonardi

Increased intraocular pressure (IOP) is the leading cause and the hallmark of Glaucoma, an asymptomatic and irreversible degenerative disease that, undetected or untreated, progresses to blindness due to optic nerve atrophy. Glaucoma is the second cause of ...
EPFL2007

A soft contact lens with a MEMS strain gage embedded for intraocular pressure monitoring

Philippe Renaud, Arnaud Bertsch, Matteo Leonardi

We propose a novel approach to intraocular pressure (IOP) measurement allowing minimal invasive continuous monitoring over prolonged periods, regardless of patient position and activities [1]. The key element of this innovative measurement method is a soft ...
2003

Feasibility of intraoperative corneal topography monitoring during photorefractive keratectomy

Demetri Psaltis

PURPOSE: We propose a feasibility study of new corneal topography technology with the aim of monitoring intraoperative corneal topography during excimer laser photorefractive keratectomy. The PAR system measures corneal topography with single grid projecti ...
2000

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