Concept

Protein family

Related publications (98)

Governance of innovation in the European railway sector

The European railway sector has undergone major transformations over the past two decades. Domestic reforms have been buttressed by European directives aimed at creating a single European railway market. In this new environment roles have been significantl ...

2010

Homing endonucleases: from basics to therapeutic applications

Homing endonucleases (HE) are double-stranded DNAses that target large recognition sites (12-40 bp). HE-encoding sequences are usually embedded in either introns or inteins. Their recognition sites are extremely rare, with none or only a few of these sites ...

Springer Verlag2009

Complex networks

Cécile Caretta Cartozo

The last decade has witnessed a fundamental change in the role of network theory. Side by side with the increasing relevance of interdisciplinarity, this ensemble of mathematical tools and methods has known such a success and such a wide range of different ...

EPFL2009

SS-SSIM and MS-SSIM for digital cinema applications

Touradj Ebrahimi

One of the key issues for a successful roll out of digital cinema is in the quality it offers. The most practical and least expensive way of measuring quality of multimedia content is through the use of objective metrics. In addition to the widely used obj ...

SPIE2009

Clustering protein environments for function prediction: finding PROSITE motifs in 3D

Giovanni De Micheli

Background: Structural genomics initiatives are producing increasing numbers of three-dimensional (3D) structures for which there is little functional information. Structure-based annotation of molecular function is therefore becoming critical. We previous ...

BioMed Central2007

Tandem Mass Spectrometry Protein Identification on a PC Grid

Markus Müller, Dominique Zosso, Ruedi Aebersold

We present a method to grid-enable tandem mass spectrometry protein identification. The implemented parallelization strategy embeds the open-source x!tandem tool in a grid-enabled workflow. This allows rapid analysis of largescale mass spectrometry experim ...

IOS Press2007

Modeling the Isoelectric Focusing of Peptides in an OFFGEL Multicompartment Cell

Hubert Girault, Niels Erik Lion, Hoang-Trang Lam

In proteomic analysis of complex samples at the peptide level (termed shotgun proteomics), an effective prefractionation is crucial to decrease the complexity of the peptide mixture for further analysis. In this perspective, the high-resolving power of the ...

American Chemical Society2007

InterPro, progress and status in 2005

Philipp Bucher, Amos Bairoch

InterPro, an integrated documentation resource of protein families, domains and functional sites, was created to integrate the major protein signature databases. Currently, it includes PROSITE, Pfam, PRINTS, ProDom, SMART, TIGRFAMs, PIRSF and SUPERFAMILY. ...

2005

On-Line Counting of Cysteine Residues in Peptides during Electrospray Ionization by Electrogenerated Tags and Their Application to Protein Identification

Hubert Girault, Niels Erik Lion, Christophe Roussel, Loïc Dayon, Michel Prudent

The electrochemically induced mass spectrometric tagging of cysteines by substituted hydroquinones was studied for peptides in a classical electrospray solvent (i.e., MeOH/H2O/AcOH 50/49/1). The tagging efficiency was tested with different hydroquinone com ...

2005

Stealth proteins: in silico identification of a novel protein family rendering bacterial pathogens invisible to host immune defense

Philipp Bucher

There are a variety of bacterial defense strategies to survive in a hostile environment. Generation of extracellular polysaccharides has proved to be a simple but effective strategy against the host's innate immune system. A comparative genomics approach l ...

2005

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