Publications related to Genistein

Upregulation of the ERR γ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis

Emerging evidence suggest that transcription factors play multiple roles in the development of pancreatitis, a necroinflammatory condition lacking specific therapy. Estrogen-related receptor γ (ERRγ), a pleiotropic transcription factor, has been reported t ...

NATL ACAD SCIENCES2023

Clofarabine Commandeers the RNR-alpha-ZRANB3 Nuclear Signaling Axis

Yimon Aye, Yi Zhao

Ribonucleotide reductase (RNR) is an essential enzyme in DNA biogenesis and a target of several chemotherapeutics. Here, we investigate how antileukemic drugs (e.g., clofarabine [CIF]) that target one of the two subunits of RNR, RNR-alpha, affect noncanoni ...

CELL PRESS2020

Genistein increases the thermogenic program of subcutaneous WAT and increases energy expenditure in mice

Lilia Noriega Lopez, Laura Alejandra Velazquez Villegas

White adipose tissue (WAT) can differentiate into beige adipose tissue by the browning process. Some polyphenols, including isoflavones, particularly genistein, are suggested to increase the expression of browning markers. There is evidence that consumptio ...

ELSEVIER SCIENCE INC2019

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice

Johan Auwerx, Kristina Schoonjans, Dongryeol Ryu, Xu Wang, Adriano Maida

Nuclear receptor corepressor 1 (NCoR1) is a transcriptional coregulator that has wide-ranging effects on gene expression patterns. In the liver, NCoR1 represses lipid synthesis in the fasting state, whereas it inhibits activation of peroxisome proliferator ...

Wiley-Blackwell2015

Instrument intercomparison in the pulsed neutron fieldsat the CERN HiRadMat facility

Nikolaos Charitonidis, Daniel Perrin

An intercomparison of the performances of active neutron detectors was carried out in pulsed neutron fields in the new HiRadMat facility at CERN. Five detectors were employed: four of them (two ionization chambers and two rem counters) are routinely employ ...

Pergamon-Elsevier Science Ltd2014

In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice

Johan Auwerx

Peroxisome proliferator-activated receptors (PPARs) have been revealed as key regulators of several skin disorders. This has led to a growing interest in the development of drugs targeting PPARs as therapeutics for skin diseases. To evaluate skin PPAR acti ...

2013

Instrument intercomparison in the pulsed neutron fields at the CERN HiRadMat facility

Nikolaos Charitonidis, Daniel Perrin, Marco Silari

An intercomparison of the performances of active neutron detectors was carried out in pulsed neutron fields in the new HiRadMat facility at CERN. Five detectors were employed: four of them (two ionization chambers and two rem counters) are routinely employ ...

2013

Endoplasmic Reticulum Stress Is Important for the Manifestations of alpha-Synucleinopathy In Vivo

Bernard Schneider, Ying Liu, Philippe Guillaume Coune

Accumulation of misfolded alpha-synuclein (alpha S) is mechanistically linked to neurodegeneration in Parkinson's disease (PD) and other alpha-synucleinopathies. However, how alpha S causes neurodegeneration is unresolved. Because cellular accumulation of ...

Society for Neuroscience2012

Impaired myogenesis in estrogen-related receptor γ (ERRγ)-deficient skeletal myocytes due to oxidative stress

Johan Auwerx

Specialized contractile function and increased mitochondrial number and oxidative capacity are hallmark features of myocyte differentiation. The estrogen-related receptors (ERRs) can regulate mitochondrial biogenesis or mitochondrial enzyme expression in s ...

Federation Amer Soc Exp Biol2012

Photoactive sawhorse-type diruthenium tetracarbonyl complexes

Georges Wagnières, Frédéric Schmitt

Sawhorse-type diruthenium tetracarbonyl complexes incorporating carboxyphenyl porphyrin bridges and pyridine axial ligands have been prepared, characterized and evaluated as potential photosensitizing and chemotherapeutic agents in several human cancer cel ...

Elsevier2012

Genistein

Upregulation of the ERR γ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis

Clofarabine Commandeers the RNR-alpha-ZRANB3 Nuclear Signaling Axis

Genistein increases the thermogenic program of subcutaneous WAT and increases energy expenditure in mice

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice

Instrument intercomparison in the pulsed neutron fieldsat the CERN HiRadMat facility

In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice

Instrument intercomparison in the pulsed neutron fields at the CERN HiRadMat facility

Endoplasmic Reticulum Stress Is Important for the Manifestations of alpha-Synucleinopathy In Vivo

Impaired myogenesis in estrogen-related receptor γ (ERRγ)-deficient skeletal myocytes due to oxidative stress

Photoactive sawhorse-type diruthenium tetracarbonyl complexes

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Upregulation of the ERR γ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis

Clofarabine Commandeers the RNR-alpha-ZRANB3 Nuclear Signaling Axis

Instrument intercomparison in the pulsed neutron fieldsat the CERN HiRadMat facility

In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice

Genistein increases the thermogenic program of subcutaneous WAT and increases energy expenditure in mice

Instrument intercomparison in the pulsed neutron fields at the CERN HiRadMat facility

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice

Impaired myogenesis in estrogen-related receptor γ (ERRγ)-deficient skeletal myocytes due to oxidative stress

Endoplasmic Reticulum Stress Is Important for the Manifestations of alpha-Synucleinopathy In Vivo

Photoactive sawhorse-type diruthenium tetracarbonyl complexes