Body mass index

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Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

Kristina Schoonjans, Alessia Perino

Bile acids (BAs) improve metabolism and exert anti-obesity effects through the activation of the Takeda G protein-coupled receptor 5 (TGR5) in peripheral tissues. TGR5 is also found in the brain hypothalamus, but whether hypothalamic BA signaling is implic ...

Cell Press2021

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Jacques Fellay, Christian Hammer, Christian Axel Wandall Thorball, Monia Guidi, Thierry Buclin

Objective. There is limited data on abdominal obesity and the influence of genetics on weight change after ant iretroviral therapy (ART) initiation. We assessed body mass index (BMI) and waist hip ration (WHR) change over time in the Swiss HIV Cohort study ...

OXFORD UNIV PRESS INC2020

Turning negative into positives! Exploiting 'negative' results in Brain-Machine Interface (BMI) research

Ricardo Andres Chavarriaga Lozano, Camille Marie Jeunet

Results that do not confirm expectations are generally referred to as 'negative' results. While essential for scientific progress, they are too rarely reported in the literature - Brain-Machine Interface (BMI) research is no exception. This led us to organ ...

TAYLOR & FRANCIS LTD2019

Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice

Kristina Schoonjans, Adriano Maida

The bile acid receptor, TGR5, is a key regulator of glucose homeostasis, but the mechanisms by which TGR5 signaling improves glucose regulation are incompletely defined. In particular, TGR5 has an increasingly appreciated role in liver physiology and patho ...

2020

Protecting Mobile Food Diaries from Getting too Personal

Daniel Gatica-Perez, Lakmal Buddika Meegahapola

Smartphone applications that use passive sensing to support human health and well-being primarily rely on: (a) generating low-dimensional representations from high-dimensional data streams; (b) making inferences regarding user behavior; and (c) using those ...

Association for Computing Machinery2020

Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice

Johan Auwerx, Jun Yong Kim, Ludger Jan Elzuë Goeminne, Dongryeol Ryu

Mitochondrial dysfunction is associated with aging-mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and type 2 diabetes. Growth differentiation factor 15 (GDF15) is an important mitokine generated in r ...

2020

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

2020

Multiaxial fatigue analysis of high-strength steel welded joints using generalized local approaches

Martin Antonio René Garcia

The objective of this thesis is to improve methods for predicting the fatigue life, multiaxial or not, of mild- and more particularly high-strength steels using local approaches that have the capacity to be applicable to almost any cases, hence the term ge ...

EPFL2020

Inconsistent relationship between body weight/body mass index prior to total knee arthroplasty and the 12-year survival

Brigitte Jolles-Haeberli

Background: The primary hypothesis was that body weight (BW) and body mass index (BMI) significantly impact the long-term survival rate after implantation of a mobile bearing total knee arthroplasty (TKA). ...

ELSEVIER2019

The role of somatosensory feedback for brain-machine interfaces applications

Tiffany Corbet

Brain-machine interfaces (BMI) based on motor imagery (MI) have emerged as a promising approach to enhance motor skills and restore motor functions. However, the efficacy and efficiency of BMI systems remain limited. The current lack of usability can be ex ...

EPFL2019

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Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Jacques Fellay, Christian Hammer, Christian Axel Wandall Thorball, Monia Guidi, Thierry Buclin

OXFORD UNIV PRESS INC2020