A metatheory or meta-theory is a theory the subject matter of which is theory itself, for example as an analysis or description of existing theory. For mathematics and mathematical logic, a metatheory is a mathematical theory about another mathematical theory. Meta-theoretical investigations are part of the philosophy of science. The topic of metascience is an attempt to use scientific knowledge to improve the practice of science itself. The study of metatheory became widespread during the 20th century after its application to various topics, including scientific linguistics and its concept of metalanguage. Metascience Metascience is the use of scientific method to study science itself. Metascience is an attempt to increase the quality of scientific research while reducing wasted activity; it uses research methods to study how research is done or can be improved. It has been described as "research on research", "the science of science", and "a bird's eye view of science". In the words of John Ioannidis, "Science is the best thing that has happened to human beings ... but we can do it better." In 1966, an early meta-research paper examined the statistical methods of 295 papers published in ten well-known medical journals. It found that, "in almost 73% of the reports read ... conclusions were drawn when the justification for these conclusions was invalid". Meta-research during the ensuing decades found many methodological flaws, inefficiencies, and bad practices in the research of numerous scientific topics. Many scientific studies could not be reproduced, particularly those involving medicine and the so-called soft sciences. The term "replication crisis" was invented during the early 2010s as part of an increasing awareness of the problem. Measures have been implemented to address the issues revealed by metascience. These measures include the pre-registration of scientific studies and clinical trials as well as the founding of organizations such as CONSORT and the EQUATOR Network that issue guidelines for methods and reporting.

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Related concepts (3)
Metalogic
Metalogic is the study of the metatheory of logic. Whereas logic studies how logical systems can be used to construct valid and sound arguments, metalogic studies the properties of logical systems. Logic concerns the truths that may be derived using a logical system; metalogic concerns the truths that may be derived about the languages and systems that are used to express truths. The basic objects of metalogical study are formal languages, formal systems, and their interpretations.
Metamathematics
Metamathematics is the study of mathematics itself using mathematical methods. This study produces metatheories, which are mathematical theories about other mathematical theories. Emphasis on metamathematics (and perhaps the creation of the term itself) owes itself to David Hilbert's attempt to secure the foundations of mathematics in the early part of the 20th century. Metamathematics provides "a rigorous mathematical technique for investigating a great variety of foundation problems for mathematics and logic" (Kleene 1952, p.
Metaphilosophy
Metaphilosophy, sometimes called the philosophy of philosophy, is "the investigation of the nature of philosophy". Its subject matter includes the aims of philosophy, the boundaries of philosophy, and its methods. Thus, while philosophy characteristically inquires into the nature of being, the reality of objects, the possibility of knowledge, the nature of truth, and so on, metaphilosophy is the self-reflective inquiry into the nature, aims, and methods of the activity that makes these kinds of inquiries, by asking what is philosophy itself, what sorts of questions it should ask, how it might pose and answer them, and what it can achieve in doing so.

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