Publications related to Anaphase-promoting complex

Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage

Gérald Joseph Paul Lossaint, Katarina Bacevic

Although cyclin-dependent kinase 2 (Cdk2) controls the G1/S transition and promotes DNA replication, it is dispensable for cell cycle progression due to redundancy with Cdk1. Yet Cdk2 also has non-redundant functions that can be revealed in certain genetic ...

Springer Nature2017

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

Vincenzo Sorrentino

Charcot-Marie-Tooth (CMT) disease type 2 is a genetically heterogeneous group of inherited neuropathies characterized by motor and sensory deficits as a result of peripheral axonal degeneration. We recently reported a frameshift (FS) mutation in the Really ...

Oxford Univ Press2017

CO Cleavage and CO2 Functionalization under Mild Conditions by a Multimetallic CsU2 Nitride Complex

Rosario Scopelliti, Marinella Mazzanti, Lucile Sylvie Danielle Chatelain, Marta Falcone

Novel efficient chemical processes involving cheap and widely accessible carbon dioxide or carbon monoxide under mild conditions for the production of valuable chemical products are highly desirable in the current energetic context. Uranium nitride materia ...

2017

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Béatrice Kunz, Alessandra Piersigilli, Julie Deuquet Ariosa, Jérôme Bürgi

Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneous nodules, gingival hypertrophy and ...

Springer Nature2017

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Pierre Gönczy, Coralie Busso, Sachin Kotak

Accurate spindle positioning is essential for error-free cell division. The one-cell Caenorhabditis elegans embryo has proven instrumental for dissecting mechanisms governing spindle positioning. Despite important progress, how the cortical forces that act ...

2016

Anti-angiogenic properties of chlorambucil derivatives with fluorous and hydrocarbon appendages

Paul Joseph Dyson, Patrycja Nowak-Sliwinska, Catherine Marie Amélie Clavel, Emilia Paunescu

Chlorambucil (CLB) derivatives with long fluorous (referred to as 1 and 2) or hydrocarbon (3) chains have been evaluated in a series of in vitro and in vivo assays. In cell viability inhibition assays, both derivatives 2 and 3 show selective cytotoxicity t ...

Royal Society of Chemistry2016

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome

Henning Paul-Julius Stahlberg, Simone Cavadini, Radosav Svetozara Pantelic

The cullin-RING ubiquitin E3 ligase (CRL) family comprises over 200 members in humans. The COP9 signalosome complex (CSN) regulates CRLs by removing their ubiquitin-like activator NEDD8. The CUL4A-RBX1-DDB1-DDB2 complex (CRL4A(DDB2)) monitors the genome fo ...

Springer Nature2016

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

Michaël Unser, Daniel Sage, Jacques Rougemont, Viesturs Simanis, Andrea Krapp, Daniel Andreas Schmitter, Anastasia Chasapi, Ioannis Xenarios

The Schizosaccharomyces pombe septation initiation network (SIN) regulates cytokinesis, and asymmetric association of SIN proteins with the mitotic spindle pole bodies (SPBs) is important for its regulation. Here, we have used semi-automated image analysis ...

Company Of Biologists Ltd2015

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Anaphase-promoting complex

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

CO Cleavage and CO2 Functionalization under Mild Conditions by a Multimetallic CsU2 Nitride Complex

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Anti-angiogenic properties of chlorambucil derivatives with fluorous and hydrocarbon appendages

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome

Eukaryotic transcription factor binding kinetics

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

Graph Chatbot

Chat with Graph Search

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

Aurora A kinase regulates proper spindle positioning in C-elegans and in human cells

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome

Anti-angiogenic properties of chlorambucil derivatives with fluorous and hydrocarbon appendages

CO Cleavage and CO2 Functionalization under Mild Conditions by a Multimetallic CsU2 Nitride Complex

Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome

Eukaryotic transcription factor binding kinetics