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The realistic reconstruction of hair motion is challenging because of hair’s complex occlusion, lack of a well-defined surface, and non-Lambertian material. We present a system for passive capture of dynamic hair performances using a set of high-speed vide ...
Melanocyte stem cells in the bulge area of hair follicles are responsible for hair pigmentation, and defects in them cause hair graying. Here we describe the process of melanocyte stem cell entry into the quiescent state and show that niche-derived transfo ...
c-Myc is involved in the control of diverse cellular processes and implicated in the maintenance of different tissues including the neural crest. Here we report that c-Myc is particularly important for pigment cell development and homeostasis. Targeting c- ...
SPINK5 (serine protease inhibitor Kazal-type 5) encodes the proteinase inhibitor LEKTI (lympho-epithelial Kazal-type related inhibitor). In skin, LEKTI expression is restricted to the stratum granulosum of the epidermis and the inner root sheath of hair fo ...
In this paper we present an electrical model of the inner hair cell based on an improved mathematical model. The model is implemented in silicon in the current domain using translinear circuits. It improves on previous models by taking into consideration t ...
Epithelial-mesenchymal interactions are key to skin morphogenesis and homeostasis. We report that maintenance of the hair follicle keratinocyte cell fate is defective in mice with mesenchymal deletion of the CSL/RBP-Jkappa gene, the effector of "canonical" ...
The present invention is related to new molecules capable of interacting with target of rapamycin (TOR) transcriptional complex. In particular, the present invention provides novel nucleic acid molecules, processes for production thereof, kits containing t ...
To simulate realistic crowds of virtual humans in real time, three main requirements need satisfaction. First of all, quantity, i.e., the ability to simulate thousands of characters. Secondly, quality, because each virtual human composing a crowd needs to ...
Analysis of the 3D structure of a biological sample is an important step to model cell and tissue dynamics. As a model system, we set up to determine the number of nuclei in a follicular papilla using confocal imaging and 3D computer reconstruction. The fo ...
In hair follicles, dermal papilla (DP) and dermal sheath (DS) cells exhibit striking levels of plasticity, as each can regenerate both cell types. Here, we show that thrombin induces a phosphoinositide 3-kinase (PI3K)-Akt pathway-dependent acquisition of D ...
