Concept

Intermediate filament

Related publications (73)

Universal Casimir attraction between filaments at the cell scale

The electromagnetic Casimir interaction between dielectric objects immersed in salted water includes a universal contribution that is not screened by the solvent and therefore long-ranged. Here, we study the geometry of two parallel dielectric cylinders. W ...

Bristol2024

Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological Architectures

Majed Chergui, Katrin Elisabeth Oberhofer

Networks of tryptophan (Trp)& horbar;an aromatic amino acid with strong fluorescence response & horbar;are ubiquitous in biological systems, forming diverse architectures in transmembrane proteins, cytoskeletal filaments, subneuronal elements, photorecepto ...

Amer Chemical Soc2024

Hierarchical Protofilament Intertwining Rules the Formation of Mixed-Curvature Amyloid Polymorphs

Giovanni Dietler, Henning Paul-Julius Stahlberg, Meltem Tatli, Francesco Simone Ruggeri, Jiangtao Zhou, Salvatore Assenza, Raffaele Mezzenga

Amyloid polymorphism is a hallmark of almost all amyloid species, yet the mechanisms underlying the formation of amyloid polymorphs and their complex architectures remain elusive. Commonly, two main mesoscopic topologies are found in amyloid polymorphs cha ...

Wiley2024

AAV9-mediated SMN gene therapy rescues cardiac desmin but not lamin A/C and elastin dysregulation in Smn(2B/-) spinal muscular atrophy mice

Bernard Schneider

Structural, functional and molecular cardiac defects have been reported in spinal muscular atrophy (SMA) patients and mouse models. Previous quantitative proteomics analyses demonstrated widespread molecular defects in the severe Taiwanese SMA mouse model. ...

OXFORD UNIV PRESS2023

High-efficiency non-ablative UV laser nano-scale processing of fused silica by stable filamentation

Yves Bellouard, Olivier Bernard, Benedikt Hermann, Luca Muscarella

Over the last decades, three-dimensional micro-manufacturing of fused silica via near-infrared ultrafast laser exposure combined with an etching step has become an established technique for producing complex three-dimensional components. Here, we explore t ...

2023

Pde-Constrained Optimization For Nuclear Mechanics

We propose an image based PDE-constrained optimisation framework to compute the dynamical quantities of a cell nucleus undergoing deformation. It allows retrieving the displacement, strain and stress at each pixel of the nuclear domain, as well as the trac ...

IEEE2022

Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1

Rudolf Hovius, Beat Fierz

The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet how thi ...

ELIFE SCIENCES PUBLICATIONS LTD2020

Scrape-off layer transport and filament characteristics in high-density tokamak regimes

Holger Reimerdes, Benoît Labit, Christian Gabriel Theiler, Alexander Karpushov, Nicola Vianello, Cedric Kar-Wai Tsui, Kevin Henricus Annemarie Verhaegh, Roberto Maurizio, Hugo De Oliveira

A detailed cross-device investigation on the role of filamentary dynamics in high-density regimes has been performed within the EUROfusion framework, comparing the ASDEX Upgrade (AUG) and TCV tokamaks. Both devices run density ramp experiments at different ...

2020

Spin cascade and doming in ferric hemes: Femtosecond X-ray absorption and X-ray emission studies

Majed Chergui, Oliviero Cannelli, Christopher Alexander Arrell, Wojciech Gawelda, Giulia Fulvia Mancini, Frederico Alves Lima, Camila Bacellar Cases Da Silveira, Dominik Kinschel, Rebecca Ann Ingle, Jérémy Raymond Jean Maurice Rouxel, Samuel Menzi

The structure-function relationship is at the heart of biology, and major protein deformations are correlated to specific functions. For ferrous heme proteins, doming is associated with the respiratory function in hemoglobin and myoglobins. Cytochrome c (C ...

NATL ACAD SCIENCES2020

A Magnet-Based Timing System to Detect Gate Crossings in Alpine Ski Racing

Kamiar Aminian, Benedikt Fasel

In alpine skiing, intermediate times are usually measured with photocells. However, for practical reasons, the number of intermediate cells is limited to three⁻four, making a detailed timing analysis difficult. In this paper, we propose and validate a magn ...

2019

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