Publications related to Endosome

Sphingolipid metabolic flow controls phosphoinositide turnover at the trans ‐Golgi network

Giovanni D'Angelo, Howard Riezman, Riccardo Rizzo

Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre- and post-Golgi compartments being poor and rich in sphingolipids, respectively. Due to this different sphingolipid conten ...

2017

Formation of Large Hypericin Aggregates in Giant Unilamellar Vesicles-Experiments and Modeling

Jaroslava Joniová, Veronika Huntosova

The incorporation of hypericin (Hyp) from aqueous solutions into giant unilamellar vesicle (GUV) membranes has been studied experimentally and by means of kinetic Monte Carlo modeling. The time evolution of Hyp fluorescence originating from Hyp monomers di ...

Cell Press2017

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue, Xiaomei Li

Background: Silver nanoparticles (AgNP) are widely applied and can, upon use, be released into the aquatic environment. This raises concerns about potential impacts of AgNP on aquatic organisms. We here present a side by side comparison of the interaction ...

Biomed Central Ltd2017

Discovery and characterization of novel stable tau oligomeric complexes: Implications for the role of Tau/phospholipid interactions in regulating its functions in health and disease

Hilal Lashuel, Anne-Laure Mahul Mellier, Nadine Aït Bouziad, Gizem Zorludemir

The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer's disease. Although Tau interaction with membranes is thought to affect some of its physiological functions and its aggregation properties, the sequence determinan ...

Nature Publishing Group2017

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Harm-Anton Klok, Claudia Battistella

Inhibition of P-glycoprotein (P-gp) transporter is an attractive approach for the reversion of cancer-associated multidrug resistance (MDR). Poly(N-(2-hydroxypropyl) methacrylamide) (PHPMA)-based carriers that are able to release the anticancer drug doxoru ...

2017

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

Christian Sieben

After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to release ...

Public Library Science2016

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

Jeffrey Alan Hubbell, Steinunn Baekkeskov Hanahan, Chiara Cianciaruso, Miriella Carmela Pasquier, Edward Allen Phelps

Pancreatic islet β-cells are particularly susceptible to endoplasmic reticulum (ER) stress, which is implicated in β-cell dysfunction and loss during the pathogenesis of type 1 diabetes (T1D). The peripheral membrane protein GAD65 is an autoantigen in huma ...

Amer Diabetes Assoc2016

The Ins and Outs of Anthrax Toxin

Françoise Gisou van der Goot Grunberg

Anthrax is a severe, although rather rare, infectious disease that is caused by the Gram-positive, spore-forming bacterium Bacillus anthracis. The infectious form is the spore and the major virulence factors of the bacterium are its poly-gamma-D-glutamic a ...

Mdpi Ag2016

Silver nanoparticle-protein interactions in intact rainbow trout gill cells

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue

Upon contact with biota, nanoparticles can bind to proteins, which coat the nanoparticles and form a nanoparticle-protein corona. Knowledge of corona proteins is therefore important for a mechanistic understanding of how nanoparticles interact with biomole ...

Royal Soc Chemistry2016

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Endosome

Sphingolipid metabolic flow controls phosphoinositide turnover at the trans ‐Golgi network

Formation of Large Hypericin Aggregates in Giant Unilamellar Vesicles-Experiments and Modeling

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison

Discovery and characterization of novel stable tau oligomeric complexes: Implications for the role of Tau/phospholipid interactions in regulating its functions in health and disease

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

The Ins and Outs of Anthrax Toxin

Silver nanoparticle-protein interactions in intact rainbow trout gill cells

Folding and Endocytosis of Anthrax Toxin Receptors

Graph Chatbot

Chat with Graph Search

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

The Ins and Outs of Anthrax Toxin

Folding and Endocytosis of Anthrax Toxin Receptors

Silver nanoparticle-protein interactions in intact rainbow trout gill cells

Formation of Large Hypericin Aggregates in Giant Unilamellar Vesicles-Experiments and Modeling

Sphingolipid metabolic flow controls phosphoinositide turnover at the trans ‐Golgi network

Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison

Discovery and characterization of novel stable tau oligomeric complexes: Implications for the role of Tau/phospholipid interactions in regulating its functions in health and disease