Publications related to MRC Laboratory of Molecular Biology

Electronic Relaxation Dynamics of UV-Photoexcited 2-Aminopurine-Thymine Base Pairs in Watson-Crick and Hoogsteen Conformations

Rebecca Ann Ingle, Hugo Jean Baptiste Marroux

The fluorescent analogue 2-aminopurine (2AP) of the canonical nucleobase adenine (6-aminopurine) base-pairs with thymine (T) without disrupting the helical structure of DNA. It therefore finds frequent use in molecular biology for probing DNA and RNA struc ...

AMER CHEMICAL SOC2019

Connection of Metallamacrocycles via Dynamic Covalent Chemistry: A Versatile Method for the Synthesis of Molecular Cages

Rosario Scopelliti, Kay Severin, Clément Schouwey, Anton Granzhan

A modular approach for the synthesis of cage structures is described. Reactions of [(arene)RuCl2]2 [arene = p-cymene, 1,3,5-C6H3Me3, 1,3,5-C6H3(i-Pr)3] with formyl-substituted 3-hydroxy-2-pyridone ligands provide trinuclear metallamacrocycles with pendant ...

2011

Assessing the structure of membrane proteins: combining different methods gives the full picture

Henning Paul-Julius Stahlberg, Andreas Engel

The rotor stoichiometry of F-ATPases has been revealed by the combined approaches of X-ray diffraction (XRD), electron crystallography, and atomic force microscopy (AFM). XRD showed the rotor from the yeast mitochondrial F-ATPase to contain 10 subunits. AF ...

Canadian Science Publishing2002

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MRC Laboratory of Molecular Biology

Electronic Relaxation Dynamics of UV-Photoexcited 2-Aminopurine-Thymine Base Pairs in Watson-Crick and Hoogsteen Conformations

Connection of Metallamacrocycles via Dynamic Covalent Chemistry: A Versatile Method for the Synthesis of Molecular Cages

Assessing the structure of membrane proteins: combining different methods gives the full picture

Molecular structure of the lipoamide dehydrogenase domain of a surface antigen from Neisseria meningitidis

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Molecular structure of the lipoamide dehydrogenase domain of a surface antigen from Neisseria meningitidis

Connection of Metallamacrocycles via Dynamic Covalent Chemistry: A Versatile Method for the Synthesis of Molecular Cages

Assessing the structure of membrane proteins: combining different methods gives the full picture