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Intact social memory forms the basis of meaningful interactions between individuals. Many factors can modulate the quality of social memory, and these have been studied in detail in rodents. Social memory, however, cannot be considered a single entity. The ...
Non volatile flash memories based on nanoparticles (nps) are one of the identified routes to a further downscaling of future CMOS technology. New features such as Coulomb blockade and quantized charging effects can appear at room temperature only for a lim ...
This thesis analyses the city of Buenos Aires as a lived space in its historical context, based on my childhood memories. It characterizes the specific Stimmung that colours the urban and suburban spaces of Buenos Aires in the XIXth and XXth century. I ach ...
We present DBToaster, a novel query compilation framework for producing high performance compiled query executors that incrementally and continuously answer standing aggregate queries using in-memory views. DBToaster targets applications that require effic ...
Complex brain diseases and neurological disorders in human generally result from the disturbance of multiple genes and signaling pathways. These disturbances may derive from mutations, deletions, translocations or rearrangements of specific gene(s). Howeve ...
This study analyzes three project process for the reconstruction of urban areas destroyed by natural disaster or armed conflict: the village of Gondo in Switzerland, partially destroyed by a landslide, has been refurbished following an architectural compet ...
PC7 belongs to the proprotein convertase family, whose members are implicated in the cleavage of secretory precursors. The in vivo function of PC7 is unknown. Herein, we find that the precursor proBDNF is processed into mature BDNF in COS-1 cells coexpress ...
Alzheimer's disease (AD) is the most common cause of dementia, and is characterized by memory loss and cognitive decline, as well as amyloid β (Aβ) accumulation, and progressive neurodegeneration. Cdk5 is a proline-directed serine/threonine kinase whose ac ...
NR2E3, a photoreceptor, specific nuclear receptor (PNR), represses cone-specific genes and activates several rod-specific genes. In humans, mutations in NR2E3 have been associated with the recessively-inherited enhanced short-wavelength sensitive Scone syn ...
In subunit vaccines, strong CD8(+) T-cell responses are desired, yet they are elusive at reasonable adjuvant doses. We show that targeting adjuvant to the lymph node (LN) via ultrasmall polymeric nanoparticles (NPs), which rapidly drain to the LN after int ...