Concept

Low-density lipoprotein

Related publications (182)

Additive manufacturing of hierarchical injectable scaffolds for tissue engineering

Philippe Renaud, Niccolo Piacentini, Thomas Michael Braschler

We present a 3D-printing technology allowing free-form fabrication of centimetre-scale injectable structures for minimally invasive delivery. They result from the combination of 3D printing onto a cryogenic substrate and optimisation of carboxymethylcellul ...

2018

Structure of the human multidrug transporter ABCG2

Henning Paul-Julius Stahlberg

ABCG2 is a constitutively expressed ATP-binding cassette (ABC) transporter that protects many tissues against xenobiotic molecules. Its activity affects the pharmacokinetics of commonly used drugs and limits the delivery of therapeutics into tumour cells, ...

Springer Nature2017

Associations between Daily Walking and Subclinical Health Markers in a Swiss City

Vincent Kaufmann, Emmanuel Pierre Jean Ravalet, Idris Guessous, Derek Pierre Christie

Every year, the Health Bus (Bus Santé) enables a representative sample of around 1000 members of the non-institutionalised adult population of Geneva, Switzerland, to undergo a health evaluation including physical measurements, blood tests and questionnair ...

2017

Role of ERK1/2 activation and nNOS uncoupling on endothelial dysfunction induced by lysophosphatidylcholine

Nikolaos Stergiopoulos, Luciano Dos Santos Aggum Capettini

Background and aims: Lysophosphatidylcholine (LPC) - a main component of oxidized LDL -is involved in endothelial dysfunction that precedes atherosclerosis, with an increased superoxide anions and a reduced NO production via endothelial NO synthase (eNOS) ...

Elsevier2017

Spatial distribution and biological effects of trace metals (Cu, Zn, Pb, Cd) and organic micropollutants (PCBs, PAHs) in mussels Mytilus galloprovincialis along the Algerian west coast

Dominique Grandjean, Luiz Felippe De Alencastro

Native mussels Mytilus galloprovincialis are used as bioindicator organisms to assess the concentration levels and toxic effects of persistent chemicals, polychlorobiphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and heavy metals using biomarker ...

Elsevier2017

Strong paramagnon scattering in single atom Pd contacts

Klaus Kern, Markus Ternes, Uta Schlickum, Peter Wahl, Ivan Pentegov, Verena Katharina Schendel

Among all transition metals, palladium (Pd) has the highest density of states at the Fermi energy at low temperatures yet does not fulfill the Stoner criterion for ferromagnetism. However, close proximity to magnetism renders it a nearly ferromagnetic meta ...

Amer Physical Soc2017

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP

Henning Paul-Julius Stahlberg

The cholesteryl ester transfer protein (CETP) enables the transfer of cholesteryl ester (CE) from high density lipoproteins (HDL) to low-density lipoproteins (LDL) in the plasma compartment. CETP inhibition raises plasma levels of HDL cholesterol; a ternar ...

Elsevier BV2016

Preparation and Characterization of Stable -Synuclein Lipoprotein Particles

Henning Paul-Julius Stahlberg

Multiple neurodegenerative diseases are caused by the aggregation of the human -Synuclein (-Syn) protein. -Syn possesses high structural plasticity and the capability of interacting with membranes. Both features are not only essential for its physiological ...

American Society for Biochemistry & Molecular Biology (ASBMB)2016

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

Henning Paul-Julius Stahlberg

High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers. Mature HDL particles destined for the liver develop through the formation of intermediate discoidal HDL particles, which are the primary acceptors for cholesterol. Her ...

Springer Nature2016

Computational fluid dynamics with stents: quantitative comparison with particle image velocimetry for three commercial off the shelf intracranial stents

Mohamed Farhat, Pierre Bouillot, Hasan Yilmaz

Background and purpose Validation of computational fluid dynamics (CFD) in stented intracranial aneurysms (IAs) is still lacking, to reliably predict prone to occlusion hemodynamics, probing, in particular, velocity reduction, and flow pattern changes. Thi ...

Bmj Publishing Group2016

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