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Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, is considered an attractive therapeutic target in multiple inflammatory and autoimmune disorders. In addition to its known biologic activities, MIF can also function as a tautomerase ...
American Society for Biochemistry and Molecular Biology2010
A decision tree has been developed for evaluating risks posed by combined exposures to multiple chemicals. The decision tree divides combined exposures of humans and ecological receptors into groups where one or more components are a concern by themselves, ...
The Nuclear Magnetic Resonance (NMR) is an extraordinary tool to understand molecular structures. Its main limitation resides in its relatively low sensitivity when compared with other physico-chemical methods such as Mass Spectrometry (MS) or Optical Spec ...
Reversible protein phosphorylation is a major regulation mechanism of fundamental biological processes, not only in eukaryotes but also in bacteria. A growing body of evidence suggests that Ser/Thr phosphorylation play important roles in the physiology and ...
The impacts of the 30 active substances, most used in Costa Rica (reference year 1998), are evaluated using two models originally developed to support comparative assertions in the context of the life cycle assessment: the multimedia fate, exposure and eff ...
We have studied the vibrational properties of CO adsorbed on platinum and platinum-ruthenium surfaces using density-functional perturbation theory within the Perdew-Burke-Ernzerhof generalized-gradient approximation. The calculated C-O stretching frequenci ...
In this paper the effect of varying temperature, pressure and chemical precursors on the vapour-liquid-solid (VLS) growth of silicon nanowires (Si NWs) have been investigated. Some aspects of nucleation and growth mechanisms are discussed. Control on Si NW ...
The neurotransmitter noradrenaline (NA) plays a pivotal role in immune regulation. Here we used the selective neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) to investigate the impact of central NA depletion on cytokine production by spleni ...
The multicellular structure of biological organisms and the interpretation in each of their cells of a chemical program (the DNA string or genome) is the source of inspiration for the Embryonics (embryonic electronics) project, whose final objective is the ...
In large-eddy simulations of atmospheric boundary layer turbulence, the lumped coefficient in the eddy-diffusion subgrid-scale (SGS) model is known to depend on scale for the case of inert scalars. This scale dependence is predominant near the surface. In ...
