Concept
Transamination
Related publications (6)
Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125
Hilal Lashuel, Michel Prudent, Bruno Claude Daniel Fauvet, Mirva Hejjaoui, Filip Vercruysse, Yao Zhang
Despite increasing evidence that supports the role of different post-translational modifications (PTMs) in modulating α-synuclein (α-syn) aggregation and toxicity, relatively little is known about the functional consequences of each modification and whethe ...
2012Synthesis of calcium sensors for labelling fusion proteins-synthesis of modified prolines using aza naked sugar methodology
Synthesis of Modified Prolines using aza naked sugar methodology R and S-prolines are secondary, cyclic, pyrrolidine-based amino acids. Proline demonstrated excellent catalytic activity to promote enantio- and diatereoselective, intra- and intermolecular c ...
EPFL2008Chiral recognition and supramolecular self-assembly of adsorbed amino acids and dipeptides at the submolecular level
This thesis deals with the supramolecular organization of chiral aminoacids and dipeptides on metal surfaces. The emergence of homochirality in biomolecular systems is one of the most intriguing open questions of Nature. The self-assembly and amplification ...
EPFL2008Evaluation of brain mitochondrial glutamate and alpha-ketoglutarate transport under physiologic conditions
Some models of brain energy metabolism used to interpret in vivo (13)C nuclear magnetic resonance spectroscopic data assume that intramitochondrial alpha-ketoglutarate is in rapid isotopic equilibrium with total brain glutamate, most of which is cytosolic. ...
Wiley-Blackwell2005Toward dynamic isotopomer analysis in the rat brain in vivo: automatic quantitation of 13C NMR spectra using LCModel
The LCModel method was adapted to analyze localized in vivo (13)C NMR spectra obtained from the rat brain in vivo at 9.4 T. Prior knowledge of chemical-shifts, J-coupling constants and J-evolution was included in the analysis. Up to 50 different isotopomer ...
Wiley-Blackwell2003Mechanical characterization of bone from the tissue down to the lamellar level by means of nanoindentation
Osteoporosis has become an important health and economic problem of our aging western society. This metabolic illness leads to a net bone loss and to a deterioration of trabecular architecture. Motivated by the fact that osteoporosis may also result in a d ...
EPFL2002