Concept
Rhinitis
Related publications (20)
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy
Jacques Fellay, Flavia Aurelia Shoko Hodel
Infectious agents contribute significantly to the global burden of diseases through both acute infection and their chronic sequelae. We leveraged the UK Biobank to identify genetic loci that influence humoral immune response to multiple infections. From 45 ...
Cambridge2024Microbiome and Allergy
Allergic diseases including asthma, rhinitis, and food allergies affect an ever-increasing number of patients particularly in industrialized countries. Despite a role for genetic susceptibility in the development of allergies, environmental factors are inc ...
Academic Press2016The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation
Jacques Rougemont, Laure Menin, Nicola Harris, Alessandra Piersigilli, Benjamin John Marsland, Mario Michael Zaiss, Ilaria Mosconi, Lalit Kumar Dubey, Alexis Rapin, Luc Xavier Marie Lebon, Andrew J. Macpherson
Intestinal helminths are potent regulators of their host's immune system and can ameliorate inflammatory diseases such as allergic asthma. In the present study we have assessed whether this anti-inflammatory activity was purely intrinsic to helminths, or w ...
Elsevier2015Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation
Nicola Harris, Benjamin John Marsland, Ilaria Mosconi
BackgroundThymic stromal lymphopoietin (TSLP) is a cytokine primarily produced by epithelial cells, which has been shown to be a potent inducer of T-helper 2 (Th2)-type responses. However, TSLP has pleiotropic effects upon immune cells, and although extens ...
Wiley-Blackwell2014