Jieping Zhu
Five bonds form in one pot, from three well-designed yet readily accessible substrates. Simply mixing an o-alkynyl aniline, e.g., 2-H2NC6H4C==CCO2Me, an aldehyde, e.g., heptanal, and ammonium chloride in toluene at room temp., followed by addn. of an isocy ...
2002