Concept
Secondary treatment
Related people (99)
Johan Auwerx
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Florian Frédéric Vincent Breider
Florian Breider obtained his PhD in the field of the stable isotope biogeochemistry from the University of Neuchatel in 2013. This was followed by seven months of postdoc at EPFL in the Atmospheric Particles Research Laboratory and two years as research associate at Tokyo Institute of Technology (Japan) where he conducted studies on nitrous oxide biogeochemistry in oceans. From 2015 to 2018, he was research scientist in the Laboratory for Water Quality and Treatment at EPFL where he conducted research on disinfection by-products and antibiotic resistant bacteria. Since May 2018, he is director of the Central Environmental Laboratory at the Institute of Environmental Engineering of EPFL.
Christian Ludwig
2005 - today: Adjunct Professor at EPFL in the field of Solid Waste Treatment and head of the Chemical Processes and Materials research group (CPM) at Paul Scherrer Institute (PSI). Joint EPFL-PSI Professorship on Solid Waste Treatment. 2000 - today: Head, Group of Chemical Processes and Materials (CPM) at Paul Scherrer Institut (PSI). In 2009 the LEM unit was closed and the CPM group is now affiliated to the Bioenergy and Catalysis Laboratory (LBK) of the Energy and Environment Research Division (ENE). Since June 2002 permanent position ("tenure"). 1997 - 1999: Senior Scientist. Paul Scherrer Institut (PSI), General Energy Research Department, Element Cycles Section. 1995 - 1997: Research Fellow. Swiss Federal Institute for Environmental Science and Technology (EAWAG), Department of Resource and Waste Management. 1993 - 1995: Post-doc Fellow. University of California Davis, Department of Land, Air, and Water Resources (LAWR). 1990 - 1993: PhD Student. University of Berne, Department of Inorganic, Analytical, and Physical Chemistry. 1989 - 1990: Master Student. University of Berne, Department of Inorganic, Analytical, and Physical Chemistry.
Stewart Cole
Professor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.