Strategy game

A strategy game or strategic game is a game (e.g. a board game) in which the players' uncoerced, and often autonomous, decision-making skills have a high significance in determining the outcome. Almost all strategy games require internal decision tree-style thinking, and typically very high situational awareness. Strategy games are also seen as a descendant of war games, and define strategy in terms of the context of war, but this is more partial. A strategy game is a game that relies primarily on strategy, and when it comes to defining what strategy is, two factors need to be taken into account: its complexity and game-scale actions, such as each placement in a Total War series. The definition of a strategy game in its cultural context should be any game that belongs to a tradition that goes back to war games, contains more strategy than the average video game, contains certain gameplay conventions, and is represented by a particular community. Although war is dominant in strategy g

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A post-modification approach to peptide foldamers

Nadja Franz, Harm-Anton Klok, Laure Menin

Hydrophilic/hydrophobic patterning is a powerful strategy to control folding in non-natural polymers/oligomers. In this contribution, we present a novel strategy for the preparation of alternating hydrophilic/hydrophobic patterned non-natural peptide foldamers. This strategy relies on the post-modification of a reactive peptide precursor that can be prepared via standard solid phase peptide synthesis without the need for side chain protective groups. The peptide scaffolds consisted of an alternating sequence of L-leucine and L-allylglycine residues. Using thiol-ene chemistry, the double bonds in the side chains of the L-allylglycine units could be post-modified with cysteamine hydrochloride, thioglycolic acid, 1-thioglycerol or 2,3,4,6-tetra-O-acetyl-thio-beta-D-glucopyranose to afford alternating hydrophilic/hydrophobic patterned peptides. In agreement with the alternating hydrophilic/hydrophobic patterned primary structure, cysteamine and thioglycolic acid post-modified octapeptides were found to adopt a beta-sheet secondary structure in basic or acidic aqueous media, respectively. The proposed synthetic approach is not only of interest to generate diverse libraries of peptide foldamers from a limited number of reactive precursor scaffolds, but may also represent an attractive, general strategy for the synthesis of peptides with complex side chain functionalities that are not easily accessible via standard solid phase techniques.

Royal Society of Chemistry2009

On the use of an Interoperability Framework in Coopetition Context

Arash Golnam, Alain Wegmann

The simultaneous cooperation and competition between companies referred to as coopetition in the strategy literature is becoming a recurring theme in the business settings. Companies cooperate with their competitors to gain access to supplementary and complementary resources and capabilities in order to create more value for the customers in order to achieve sustainable value creation and distribution. To coopete, the companies need to be interoperable. Growing globalization, competitiveness and rising environmental awareness are driving many companies to prepare and control their interoperability strategy in order to enhance their ability to interoperate. In this paper, we use an interoperability model called the Maturity Model for Enterprise Interoperability (MMEI) to the coopetition context and we present some initial thoughts on the use of this maturity model in the coopetition context.

2011

Domain-specific language model adaptation: a case study

John David Scott Dines, Petr Motlicek

Domain language model (LM) adaptation consists in re-estimating probabilities of a baseline LM to better match the peculiarities of a given broad topic of interest. To do so, a yet common strategy consists in retrieving adaptation texts from the Web based on a given domain representative seed text. In this report, we extensively study this process by analyzing the impact of numerous parameters. The domain adaptation is carried on a set of videos dealing with business and management. The achieved results mainly show which Web querying strategies perform the best and how significantly the supervision level of the adaptation process impacts the overall performances.

Idiap2011

Board game

Board games are tabletop games that typically use . These pieces are moved or placed on a pre-marked board (playing surface) and often include elements of table, card, role-playing, and miniatures

Artificial intelligence

Artificial intelligence (AI) is the intelligence of machines or software, as opposed to the intelligence of human beings or animals. AI applications include advanced web search engines (e.g., Google

Game theory

Game theory is the study of mathematical models of strategic interactions among rational agents. It has applications in all fields of social science, as well as in logic, systems science and computer

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