Concept

Hippocampus

Related publications (246)

On the origin of the MR image phase contrast: An in vivo MR microscopy study of the rat brain at 14.1 T

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Rajika Maddage

Recent studies at high magnetic fields using the phase of gradient-echo MR images have shown the ability to unveil cortical substructure in the human brain. To investigate the contrast mechanisms in phase imaging, this study extends, for the first time, ph ...

Elsevier2009

Spike-timing prediction in a neuron model with active dendrites

Wulfram Gerstner, Richard Naud, Brice Bathellier

A complete model for single neurons must reproduce correctly the firing of spikes and bursts. Yet it must remain simple enough to be tractable in large-scale simulations. We present a study of a simplified model of Layer V pyramidal cells of the cortex wit ...

2009

Migraine Aura: Retracting Particle-Like Waves in Weakly Susceptible Cortex

Nouchine Hadjikhani

Cortical spreading depression (SD) has been suggested to underlie migraine aura. Despite a precise match in speed, the spatio-temporal patterns of SD observed in animal cortex and aura symptoms mapped to the cortical surface ordinarily differ in aspects of ...

2009

Transmission and spreading of tauopathy in transgenic mouse brain

Tristan Bolmont

Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several neurodegenerative diseases, including Alzheimer's disease(1). In the disease process, neuronal tau inclusions first appear in the transentorhinal cortex from where they se ...

Nature Publishing Group2009

Functional shape of the spike-triggered adaptation

Christian Antonio Pozzorini

In computational neuroscience, it is of crucial importance to dispose of a model that is able to accurately describe the single-neuron activity. This model should be at the same time biologically relevant and computationally fast. Many different phenomenol ...

2009

Chronic stress in adulthood followed by intermittent stress impairs spatial memory and the survival of newborn hippocampal cells in aging animals: prevention by FGL, a peptide mimetic of neural cell adhesion molecule

Maria del Carmen Sandi Perez, Erika Myrna Borcel Novoa, Thomas Brionne

In this study, we examined whether chronic stress in adulthood can exert long-term effects on spatial-cognitive abilities and on the survival of newborn hippocampal cells in aging animals. Male Wistar rats were subjected to chronic unpredictable stress at ...

Lippincott, Williams & Wilkins2008

Long-term monitoring of post-stroke plasticity after transient cerebral ischemia in mice using in vivo and ex vivo diffusion tensor MRI

Pierre Magistretti

WE USED A MURINE MODEL OF TRANSIENT FOCAL CEREBRAL ISCHEMIA TO STUDY: 1) in vivo DTI long-term temporal evolution of the apparent diffusion coefficient (ADC) and diffusion fractional anisotropy (FA) at days 4, 10, 15 and 21 after stroke 2) ex vivo distribu ...

2008

AMPA receptor imaging by infrared scanning near-field optical microscopy

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Johanna Generosi, Michel Kropf

Infrared scanning near-field optical microscopy is used to detect AMPA-type glutamate receptor clusters in hippocampal neuron cells. AMPA's GluR2-subunits were marked with the fluorophore Alexa488 and high-resolution micrographs were taken at 6.25 µm wavel ...

2008

A benchmark test for a quantitative assessment of simple neuron models

Wulfram Gerstner, Richard Naud, Renaud Jolivet

Several methods and algorithms have recently been proposed that allow for the systematic evaluation of simple neuron models from intracellular or extracellular recordings. Models built in this way generate good quantitative predictions of the future activi ...

Elsevier2008

Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism

Henry Markram, Tania Rinaldi, Catherine Perrodin

The prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher-order functions related to cognition, language, sociability and emotion. The possible changes at the level of the neuronal microcircuit are ho ...

2008

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.