Concept
Upper gastrointestinal bleeding
Related publications (28)
Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions
Traditional cell cultures have long been fundamental to biological research, offering an alternative to animal models burdened by ethical constraints and procedural intricacies, often lacking relevance to human physiology and disease. Moreover, their inabi ...
EPFL2024Bioengineering functional organoid models across scales
The last two decades have seen the development of organoid models for many different tissues and organs. Organoids are three-dimensional organ-mimetics derived from stem or progenitor cells comprising various specialized cell types, resembling the architec ...
EPFL2024Bio accessibility of tire-associated organic chemicals in fish gut (Oncorhynchus mykiss): insights from an in vitro digestion model
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
Tire and Road Wear Particles (TRWP) account for an important part of the anthropogenic particles released into the environment. There are scientific knowledge gaps as to the potential bio accessibility of chemicals associated with TRWP to aquatic organisms ...
2022In Vitro Digestion of Tire Particles in a Fish Model (Oncorhynchus mykiss): Solubilization Kinetics of Heavy Metals and Effects of Food Coingestion
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
Tire and road wear particles (TRWP) have been shown to represent a large part of anthropogenic particles released into the environment. Nevertheless, the potential ecological risk of TRWP in the different environmental compartments and their potential toxi ...
2021Symptom Prediction and Mortality Risk Calculation for COVID-19 Using Machine Learning
Nahal Mansouri, Sahand Jamal Rahi
Background: Early prediction of symptoms and mortality risks for COVID-19 patients would improve healthcare outcomes, allow for the appropriate distribution of healthcare resources, reduce healthcare costs, aid in vaccine prioritization and self-isolation ...
FRONTIERS MEDIA SA2021Contactless Sleep Monitoring for Early Detection of Health Deteriorations in Community-Dwelling Older Adults: Exploratory Study
Daniel Gatica-Perez, Philipp Buluschek, Bruno Pais
Background: Population aging is posing multiple social and economic challenges to society. One such challenge is the social and economic burden related to increased health care expenditure caused by early institutionalizations. The use of modern pervasive ...
JMIR PUBLICATIONS, INC2021In-vitro digestion of Tire and Road Wear Particles: Bioavailability of metals and Polycyclic Aromatic Hydrocarbons
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
The potential impact of Tire and Road Wear Particles (TRWP) on aquatic organisms has recently gained attention since the occurrence of TRWP in the aquatic environment has been observed in surface water and sediments of numerous regions. Moreover, the inges ...
2021Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs
Christian Heinis, Xudong Kong, Jonas Alfred Karl Wilbs, Patrick Andreas Gonschorek, Simon Jan Middendorp, Christina Lamers
Inhibiting thrombosis without generating bleeding risks is a major challenge in medicine. A promising solution may be the inhibition of coagulation factor XII (FXII), because its knock-out or inhibition in animals reduced thrombosis without causing abnorma ...
2020Potential bioavailability of inorganic compounds from Tire and Road Wear Particles to fish in simulated gastric and intestinal fluids
Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset
The potential impact of Tire and Road Wear Particles (TRWP) on aquatic organisms has recently gained attention since the occurrence of TRWP in the aquatic environment has been demonstrated in surface water and sediments of numerous regions. However, data r ...
2020De novo development of proteolytically resistant therapeutic peptides for oral administration
Christian Heinis, Luciano Andres Abriata, Florence Pojer, Xudong Kong, Vanessa Carle, Jun Moriya
The oral administration of peptide drugs is hampered by their metabolic instability and limited intestinal uptake. Here, we describe a method for the generation of small target-specific peptides (less than 1,600 Da in size) that resist gastrointestinal pro ...
2020