Concept
Retinol
Related publications (28)
Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells
Cyrus Kazemiraad, Saeed Mohammadi
Vimentin is a main type 3 intermediate filament protein. It seems that abnormal expression of vimentin is contributed to the appearance of the aggressive feature of cancer cells. So that it has been reported that malignancy and epithelial-mesenchymal trans ...
SPRINGER2023Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation
Gioele La Manno, Alex Russell Lederer, Irina Khven
Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD). Despite several ongoing clinical studies, a detailed mapping of transient cellular states during in v ...
CELL PRESS2022POLYRETINA restores light responses in vivo in blind Gottingen minipigs
Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Paola Vagni, Elodie Geneviève Zollinger, Charles-Henri Puncho Jérôme Vila, Golnaz Sherafatipour
Retinal prostheses hold potential for artificial vision in blind people. Here, authors show that POLYRETINA, a large and high-density photovoltaic epiretinal device, restores light-evoked cortical responses in blind Gottingen minipigs at safe irradiance le ...
NATURE PORTFOLIO2022Optical properties and photochemical production of hydroxyl radical and singlet oxygen after ozonation of dissolved organic matter
Urs von Gunten, Frank Jonathan Leresche
This study focuses on the effects of ozonation on the optical and photochemical properties of dissolved organic matter (DOM). Upon ozonation, a decrease in light absorption properties of DOM was observed concomitantly with a large increase in singlet oxyge ...
ROYAL SOC CHEMISTRY2021Liposome nano-formulation with cationic polar lipid DOTAP and cholesterol as a suitable pH-responsive carrier for molecular therapeutic drug (all-trans retinoic acid) delivery to lung cancer cells
The molecular targeted drug ATRA demands a suitable carrier that delivers to the cancer site due to its poor bioavailability and drug resistance. ATRA, being a lipid with carboxylic acid, has been nano-formulated as a cationic lipo-ATRA with DOTAP:choleste ...
WILEY2021Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody
Henning Paul-Julius Stahlberg, Andreas Engel
Interphotoreceptor retinoid‐binding protein (IRBP) is a highly expressed protein secreted by rod and cone photoreceptors that has major roles in photoreceptor homeostasis as well as retinoid and polyunsaturated fatty acid transport between the neural retin ...
2020Distribution of the ribosome associated endonuclease Rae1 and the potential role of conserved amino acids in codon recognition
We recently identified a novel ribonuclease in Bacillus subtilis called Rae1 that cleaves mRNAs in a translation-dependent manner. Rae1 is a member of the NYN/PIN family of ribonucleases and is highly conserved in the Firmicutes, the Cyanobacteria and the ...
TAYLOR & FRANCIS INC2018Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury
Cerebral white and grey matter injury is the leading cause of an adverse neurodevelopmental outcome in prematurely born infants. High oxygen concentrations have been shown to contribute to the pathogenesis of neonatal brain damage. Here, we focused on moto ...
Hindawi Limited2016Fine structuration of low-temperature co-fired ceramic (LTCC) microreactors
Albert Renken, Paul Muralt, Lioubov Kiwi, Thomas Maeder, Bo Jiang, Julien Haber
The development of microreactors that operate under harsh conditions is always of great interest for many applications. Here we present a microfabrication process based on low-temperature co-fired ceramic (LTCC) technology for producing microreactors which ...
Royal Society of Chemistry2015Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation
Microphthalmia-associated transcription factor (MITF) is a master regulator of pigmented cell survival and differentiation with direct transcriptional links to cell cycle, apoptosis and pigmentation. In mouse, Mitf is expressed early and uniformly in optic ...
Oxford University Press2014