Concept
Anopheles
Related publications (16)
Beyond undulation! Body morphology and sensing components of elongated animals and robots reveal skills to maintain competent locomotion
Locomotion is an essential evolutive innovation of living beings that allows them to colonize and dominate the planet. As diverse as animal morphologies are (living) and were (extinct), their locomotion modalities are also diverse. In particular, animal mo ...
EPFL2023Automatic detection of potential mosquito breeding sites from aerial images acquired by unmanned aerial vehicles
The World Health Organization (WHO) has stated that effective vector control measures are critical to achieving and sustaining reduction of vector-borne infectious disease incidence. Unmanned aerial vehicles (UAVs), popularly known as drones, can be an imp ...
2021Optimization methods and objective functions for analysis of metabolic network models
Computational studies of metabolism aim to systematically analyze the metabolic behaviour of biological systems in different conditions. Genome-scale metabolic network models (GEMs) capture the connection between elements of the network by applying stoichi ...
EPFL2020The Plasmodium falciparum, Nima-related kinase Pfnek-4: a marker for asexual parasites committed to sexual differentiation
Background: Malaria parasites undergo, in the vertebrate host, a developmental switch from asexual replication to sexual differentiation leading to the formation of gametocytes, the only form able to survive in the mosquito vector. Regulation of the onset ...
Biomed Central Ltd2012Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality
Summary A Plasmodium falciparum hexose transporter (PfHT) has previously been shown to be a facilitative glucose and fructose transporter. Its expression in Xenopus laevis oocytes and the use of a glucose analogue inhibitor permitted chemical validation of ...
Wiley-Blackwell2010Disruption of the PfPK7 gene impairs schizogony and sporogony in the human malaria parasite Plasmodium falciparum
PfPK7 is an orphan protein kinase of Plasmodium falciparum with maximal homology to MEK3/6 and to fungal protein kinase A proteins in its C-terminal and N-terminal regions, respectively. We showed previously that recombinant PfPK7 is active on various subs ...
American Society for Microbiology2008Antimalarial drug discovery: targeting protein kinases
Protein kinases (PKs) are prime targets for drug discovery in a variety of diseases, including cancer and neurodegenerative pathologies. The characterisation of the kinome of the human malaria parasite Plasmodium falciparum has revealed profound divergence ...
2007Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics
The kinome of the human malaria parasite Plasmodium falciparum includes two genes encoding mitogen-activated protein kinase (MAPK) homologues, pfmap-1 and pfmap-2, but no clear orthologue of the MAPK kinase (MAPKK) family, raising the question of the mode ...
Wiley-Blackwell2007In vivo imaging enters parasitology
In vivo infection routes of parasites have remained something of a "black box", in which only snapshot views of fixed tissues are available. Clearly, there exists a strong need for imaging approaches to visualise living parasites within intact organs and a ...
Elsevier2006Lentivirus-mediated expression of glutathione peroxidase: neuroprotection in murine models of Parkinson's disease
Patrick Aebischer, Jean-Charles Bensadoun
Reactive oxygen species are considered to contribute to the pathogenesis of Parkinson's disease (PD). In order to study viral vector-mediated overexpression of the antioxidant enzyme glutathione peroxidase (GPX) as a potential neuroprotective approach in b ...
2006