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Neuroblastoma is the most common extracranial solid tumor of childhood. One important factor that predicts a favorable prognosis is the robust expression of the TRKA and p75NTR neurotrophin receptor genes. Interestingly, TRKA and p75NTR expression is often ...
The small heterodimer partner (SHP, nuclear receptor subfamily 0, group B, member 2; NR0B2) is an atypical nuclear receptor known mainly for its role in bile acid homeostasis in the enterohepatic tract. We previously showed that NR0B2 controls testicular f ...
The s- vs. p-character of title allylmetal compds. was studied via 13C NMR of R2CR1:CRCH2N (R = H, Me2CH, Me3C, R1 = R2 = H; R = R1 = H, R2 = Me; R = H, R1 = R2 = Me; M = Li, K, MgBr) and of deuterated derivs. [on SciFinder (R)] ...
The giant unicellular macroalgae exhibit an extraordinary wound repair mechanism. The rapid assimilation of cellular contents into an insoluble wound plug prevents detrimental cytoplasmic loss and limits the intrusion of extracellular components which coul ...
Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor involved in neuronal development and synaptic plasticity. Although the physiological effects of BDNF have been examined in detail, target proteins which mediate its actions remain largely un ...